TOP3A - BLM

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP3A	ENSG00000177302	No diseases in record	No drugs in record	DNA binding DNA topoisomerase activity DNA topoisomerase type I activity protein binding zinc ion binding	TOP3 (S. cerevisiae) Top3alpha (D. melanogaster)
BLM	ENSG00000197299	leukaemia lymphoma skin squamous cell other tumour types	No drugs in record	bubble DNA binding p53 binding single-stranded DNA binding ATP-dependent DNA helicase activity helicase activity protein binding ATP binding ATP-dependent helicase activity four-way junction helicase activity ATPase activity annealing helicase activity ATP-dependent 3'-5' DNA helicase activity G-quadruplex DNA binding DNA helicase activity DNA-dependent ATPase activity Y-form DNA binding	SGS1 (S. cerevisiae) him-6 (C. elegans) Blm (D. melanogaster)