SIR2

YDL042C - S. cerevisiae

Pathways

Go term Description
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GO:0017136 NAD-dependent histone deacetylase activity
GO:0032041 NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0016787 hydrolase activity
GO:0031491 nucleosome binding
GO:0008270 zinc ion binding
GO:0051287 NAD binding
GO:0070403 NAD+ binding
GO:0046872 metal ion binding
GO:0046969 NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)
GO:1990162 histone deacetylase activity (H3-K4 specific)
GO:0032129 histone deacetylase activity (H3-K9 specific)
GO:0004407 histone deacetylase activity
GO:0034739 histone deacetylase activity (H4-K16 specific)
GO:0031078 histone deacetylase activity (H3-K14 specific)

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
SIRT1 H. sapiens

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
YDL042C SIR2 YOL115W PAP2 S. cerevisiae SSL Slorth 0.936055 View
YDL042C SIR2 YOR304W ISW2 S. cerevisiae SDL Slorth 0.93601 View
YDL042C SIR2 YIL021W RPB3 S. cerevisiae SSL Slorth 0.935986 View
YDL042C SIR2 YPL153C RAD53 S. cerevisiae SDL Slorth 0.935799 View
YDL042C SIR2 YGL237C HAP2 S. cerevisiae SSL Slorth 0.935569 View
YBR234C ARC40 YDL042C SIR2 S. cerevisiae SDL Slorth 0.935292 View
YDL042C SIR2 YHR143W-A RPC10 S. cerevisiae SSL Slorth 0.935054 View
YDL042C SIR2 YML015C TAF11 S. cerevisiae SSL Slorth 0.934666 View
YDL042C SIR2 YDL155W CLB3 S. cerevisiae SSL Slorth 0.934652 View
YDL042C SIR2 YNL218W MGS1 S. cerevisiae SDL Slorth 0.934404 View
YDL042C SIR2 YOL090W MSH2 S. cerevisiae SDL Slorth 0.933939 View
YDL042C SIR2 YOL068C HST1 S. cerevisiae SSL Slorth 0.933808 View
YDL042C SIR2 YDR477W SNF1 S. cerevisiae SDL Slorth 0.933668 View
YDL042C SIR2 YMR223W UBP8 S. cerevisiae SDL Slorth 0.933318 View
YDL042C SIR2 YDR146C SWI5 S. cerevisiae SSL Slorth 0.933235 View
YDL042C SIR2 YDR440W DOT1 S. cerevisiae SSL Slorth 0.932983 View
YDL042C SIR2 YKL113C RAD27 S. cerevisiae SDL Slorth 0.932608 View
YDL042C SIR2 YDR334W SWR1 S. cerevisiae SDL Slorth 0.932445 View
YDL042C SIR2 YOR061W CKA2 S. cerevisiae SDL Slorth 0.932349 View
YDL042C SIR2 YGL112C TAF6 S. cerevisiae SSL Slorth 0.932177 View
YBR060C ORC2 YDL042C SIR2 S. cerevisiae SDL Slorth 0.93216 View
YDL042C SIR2 YNL097C PHO23 S. cerevisiae SSL Slorth 0.931861 View
YDL042C SIR2 YLR418C CDC73 S. cerevisiae SDL Slorth 0.931827 View
YDL042C SIR2 YPL209C IPL1 S. cerevisiae SSL Slorth 0.931555 View
YDL042C SIR2 YIL144W NDC80 S. cerevisiae SSL Slorth 0.931186 View
YDL042C SIR2 YJL140W RPB4 S. cerevisiae SSL Slorth 0.930829 View
YDL042C SIR2 YER016W BIM1 S. cerevisiae SSL Slorth 0.930628 View
YDL042C SIR2 YDR448W ADA2 S. cerevisiae SSL Slorth 0.930576 View
YBR058C UBP14 YDL042C SIR2 S. cerevisiae SDL Slorth 0.930541 View
YBL050W SEC17 YDL042C SIR2 S. cerevisiae SDL Slorth 0.930257 View
YDL042C SIR2 YHR099W TRA1 S. cerevisiae SDL Slorth 0.929968 View
YDL042C SIR2 YGL087C MMS2 S. cerevisiae SDL Slorth 0.929903 View
YDL042C SIR2 YDR457W TOM1 S. cerevisiae SDL Slorth 0.929891 View
YDL042C SIR2 YDR190C RVB1 S. cerevisiae SDL Slorth 0.929715 View
YBR198C TAF5 YDL042C SIR2 S. cerevisiae SSL Slorth 0.929677 View
YDL042C SIR2 YMR075W RCO1 S. cerevisiae SSL Slorth 0.929453 View
YDL042C SIR2 YNL250W RAD50 S. cerevisiae SSL Slorth 0.9294 View
YDL042C SIR2 YNL262W POL2 S. cerevisiae SDL Slorth 0.929215 View
YBR088C POL30 YDL042C SIR2 S. cerevisiae SDL Slorth 0.929143 View
YDL042C SIR2 YNL107W YAF9 S. cerevisiae SSL Slorth 0.92897 View