SIR2 - RPB3

S. cerevisiae

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
SIR2 YDL042C

No diseases in record

No drugs in record

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
NAD-dependent histone deacetylase activity
NAD-dependent histone deacetylase activity (H3-K14 specific)
hydrolase activity
nucleosome binding
zinc ion binding
NAD binding
NAD+ binding
metal ion binding
NAD-dependent histone deacetylase activity (H3-K9 specific)
NAD-dependent histone deacetylase activity (H4-K16 specific)
histone deacetylase activity (H3-K4 specific)
histone deacetylase activity (H3-K9 specific)
histone deacetylase activity
histone deacetylase activity (H4-K16 specific)
histone deacetylase activity (H3-K14 specific)
SIRT1 (H. sapiens)
RPB3 YIL021W

No diseases in record

No drugs in record

RNA polymerase II activity
RNA-directed 5'-3' RNA polymerase activity
DNA-directed 5'-3' RNA polymerase activity
metal ion binding
DNA binding
protein dimerization activity
protein binding
POLR2C (H. sapiens)