SIR2

YDL042C - S. cerevisiae

Pathways

Go term Description
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GO:0017136 NAD-dependent histone deacetylase activity
GO:0032041 NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0016787 hydrolase activity
GO:0031491 nucleosome binding
GO:0008270 zinc ion binding
GO:0051287 NAD binding
GO:0070403 NAD+ binding
GO:0046872 metal ion binding
GO:0046969 NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)
GO:1990162 histone deacetylase activity (H3-K4 specific)
GO:0032129 histone deacetylase activity (H3-K9 specific)
GO:0004407 histone deacetylase activity
GO:0034739 histone deacetylase activity (H4-K16 specific)
GO:0031078 histone deacetylase activity (H3-K14 specific)

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
SIRT1 H. sapiens

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
YDL042C SIR2 YPR120C CLB5 S. cerevisiae SDL Slorth 0.928968 View
YDL042C SIR2 YPL031C PHO85 S. cerevisiae SDL Slorth 0.92878 View
YDL042C SIR2 YLR274W MCM5 S. cerevisiae SDL Slorth 0.928523 View
YDL042C SIR2 YJR017C ESS1 S. cerevisiae SSL Slorth 0.92851 View
YDL042C SIR2 YGL244W RTF1 S. cerevisiae SSL Slorth 0.927938 View
YAL030W SNC1 YDL042C SIR2 S. cerevisiae SDL Slorth 0.927858 View
YBR235W VHC1 YDL042C SIR2 S. cerevisiae SDL Slorth 0.927472 View
YBL088C TEL1 YDL042C SIR2 S. cerevisiae SSL Slorth 0.926389 View
YDL042C SIR2 YIL126W STH1 S. cerevisiae SDL Slorth 0.926193 View
YDL015C TSC13 YDL042C SIR2 S. cerevisiae SDL Slorth 0.925758 View
YDL042C SIR2 YOL135C MED7 S. cerevisiae SSL Slorth 0.925421 View
YDL042C SIR2 YOR141C ARP8 S. cerevisiae SSL Slorth 0.924852 View
YDL042C SIR2 YPR187W RPO26 S. cerevisiae SSL Slorth 0.92484 View
YBL079W NUP170 YDL042C SIR2 S. cerevisiae SDL Slorth 0.924692 View
YBR140C IRA1 YDL042C SIR2 S. cerevisiae SDL Slorth 0.924432 View
YDL042C SIR2 YGL070C RPB9 S. cerevisiae SSL Slorth 0.923856 View
YDL019C OSH2 YDL042C SIR2 S. cerevisiae SDL Slorth 0.923681 View
YDL042C SIR2 YPR010C RPA135 S. cerevisiae SDL Slorth 0.923248 View
YDL042C SIR2 YGL150C INO80 S. cerevisiae SSL Slorth 0.922858 View
YDL042C SIR2 YER148W SPT15 S. cerevisiae SDL Slorth 0.922194 View
YDL042C SIR2 YNL261W ORC5 S. cerevisiae SSL Slorth 0.92197 View
YDL042C SIR2 YDR409W SIZ1 S. cerevisiae SSL Slorth 0.921845 View
YDL042C SIR2 YJL081C ARP4 S. cerevisiae SSL Slorth 0.921785 View
YDL042C SIR2 YFL008W SMC1 S. cerevisiae SDL Slorth 0.921665 View
YDL042C SIR2 YOL068C HST1 S. cerevisiae SDL Slorth 0.92125 View
YDL042C SIR2 YNL102W POL1 S. cerevisiae SDL Slorth 0.921225 View
YDL042C SIR2 YDR386W MUS81 S. cerevisiae SSL Slorth 0.921043 View
YDL042C SIR2 YLR321C SFH1 S. cerevisiae SSL Slorth 0.920455 View
YDL042C SIR2 YHR031C RRM3 S. cerevisiae SSL Slorth 0.920311 View
YDL042C SIR2 YGL190C CDC55 S. cerevisiae SSL Slorth 0.920252 View
YDL042C SIR2 YMR236W TAF9 S. cerevisiae SSL Slorth 0.920126 View
YDL042C SIR2 YIL143C SSL2 S. cerevisiae SDL Slorth 0.920093 View
YBR154C RPB5 YDL042C SIR2 S. cerevisiae SSL Slorth 0.919826 View
YDL042C SIR2 YNL030W HHF2 S. cerevisiae SSL Slorth 0.919636 View
YDL042C SIR2 YNL031C HHT2 S. cerevisiae SSL Slorth 0.91958 View
YDL017W CDC7 YDL042C SIR2 S. cerevisiae SDL Slorth 0.918603 View
YDL042C SIR2 YPL232W SSO1 S. cerevisiae SDL Slorth 0.918155 View
YAL012W CYS3 YDL042C SIR2 S. cerevisiae SDL Slorth 0.917777 View
YDL042C SIR2 YER177W BMH1 S. cerevisiae SDL Slorth 0.917168 View
YDL042C SIR2 YDR334W SWR1 S. cerevisiae SSL Slorth 0.917072 View