SIR2 - PHO85

S. cerevisiae

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
SIR2 YDL042C

No diseases in record

No drugs in record

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
NAD-dependent histone deacetylase activity
NAD-dependent histone deacetylase activity (H3-K14 specific)
hydrolase activity
nucleosome binding
zinc ion binding
NAD binding
NAD+ binding
metal ion binding
NAD-dependent histone deacetylase activity (H3-K9 specific)
NAD-dependent histone deacetylase activity (H4-K16 specific)
histone deacetylase activity (H3-K4 specific)
histone deacetylase activity (H3-K9 specific)
histone deacetylase activity
histone deacetylase activity (H4-K16 specific)
histone deacetylase activity (H3-K14 specific)
SIRT1 (H. sapiens)
PHO85 YPL031C

No diseases in record

No drugs in record

cyclin-dependent protein serine/threonine kinase activity
ATP binding
transferase activity
kinase activity
protein kinase activity
nucleotide binding
protein serine/threonine kinase activity
CDK16 (H. sapiens)
CDK18 (H. sapiens)
CDK14 (H. sapiens)
CDK17 (H. sapiens)
CDK15 (H. sapiens)