SIR2 - UBP8

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SIR2	YDL042C	No diseases in record	No drugs in record	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides NAD-dependent histone deacetylase activity NAD-dependent histone deacetylase activity (H3-K14 specific) hydrolase activity nucleosome binding zinc ion binding NAD binding NAD+ binding metal ion binding NAD-dependent histone deacetylase activity (H3-K9 specific) NAD-dependent histone deacetylase activity (H4-K16 specific) histone deacetylase activity (H3-K4 specific) histone deacetylase activity (H3-K9 specific) histone deacetylase activity histone deacetylase activity (H4-K16 specific) histone deacetylase activity (H3-K14 specific)	SIRT1 (H. sapiens)
UBP8	YMR223W	No diseases in record	No drugs in record	protein complex scaffold activity zinc ion binding thiol-dependent ubiquitinyl hydrolase activity thiol-dependent ubiquitin-specific protease activity peptidase activity cysteine-type peptidase activity metal ion binding hydrolase activity	USP36 (H. sapiens) USP22 (H. sapiens) USP42 (H. sapiens) USP44 (H. sapiens) USP3 (H. sapiens) USP17L22 (H. sapiens) USP17L2 (H. sapiens) USP51 (H. sapiens)