PARP1

ENSG00000143799 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0003910 DNA ligase (ATP) activity
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0030331 estrogen receptor binding
GO:0042802 identical protein binding
GO:0042826 histone deacetylase binding
GO:0047485 protein N-terminus binding
GO:0051287 NAD binding
GO:0070412 R-SMAD binding

Drugs

Drug name Description
OLAPARIB PARP 1, 2 & 3 inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
Parp D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000143799 PARP1 ENSG00000151729 SLC25A4 H. sapiens SDL Slorth 0.949686 View
ENSG00000138468 SENP7 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.949669 View
ENSG00000143799 PARP1 ENSG00000168148 HIST3H3 H. sapiens SSL Slorth 0.949538 View
ENSG00000143799 PARP1 ENSG00000173801 JUP H. sapiens SDL Slorth 0.949517 View
ENSG00000124762 CDKN1A ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.949482 View
ENSG00000113712 CSNK1A1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.949461 View
ENSG00000143799 PARP1 ENSG00000198700 IPO9 H. sapiens SSL Slorth 0.949407 View
ENSG00000143799 PARP1 ENSG00000183684 ALYREF H. sapiens SSL Slorth 0.949374 View
ENSG00000143799 PARP1 ENSG00000164104 HMGB2 H. sapiens SSL Slorth 0.949314 View
ENSG00000105325 FZR1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.949302 View
ENSG00000143799 PARP1 ENSG00000162298 SYVN1 H. sapiens SSL Slorth 0.949293 View
ENSG00000143799 PARP1 ENSG00000196628 TCF4 H. sapiens SDL Slorth 0.949293 View
ENSG00000108924 HLF ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.949206 View
ENSG00000143799 PARP1 ENSG00000164754 RAD21 H. sapiens SSL Slorth 0.949134 View
ENSG00000143799 PARP1 ENSG00000158987 RAPGEF6 H. sapiens SDL Slorth 0.949073 View
ENSG00000143799 PARP1 ENSG00000152684 PELO H. sapiens SDL Slorth 0.948983 View
ENSG00000136518 ACTL6A ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.948875 View
ENSG00000143799 PARP1 ENSG00000167085 PHB H. sapiens SSL Slorth 0.948834 View
ENSG00000143799 PARP1 ENSG00000198793 MTOR H. sapiens SDL Slorth 0.94883 View
ENSG00000143799 PARP1 ENSG00000162409 PRKAA2 H. sapiens SDL Slorth 0.948808 View
ENSG00000143799 PARP1 ENSG00000163625 WDFY3 H. sapiens SDL Slorth 0.948701 View
ENSG00000143799 PARP1 ENSG00000159496 RGL4 H. sapiens SDL Slorth 0.94863 View
ENSG00000099364 FBXL19 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.948593 View
ENSG00000143799 PARP1 ENSG00000154237 LRRK1 H. sapiens SDL Slorth 0.948549 View
ENSG00000143799 PARP1 ENSG00000198373 WWP2 H. sapiens SDL Slorth 0.948345 View
ENSG00000143799 PARP1 ENSG00000186716 BCR H. sapiens SSL Slorth 0.948288 View
ENSG00000141564 RPTOR ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.948266 View
ENSG00000143799 PARP1 ENSG00000169252 ADRB2 H. sapiens SDL Slorth 0.948252 View
ENSG00000073584 SMARCE1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.948246 View
ENSG00000143799 PARP1 ENSG00000161960 EIF4A1 H. sapiens SSL Slorth 0.948243 View
ENSG00000143756 FBXO28 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.948237 View
ENSG00000107872 FBXL15 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.948237 View
ENSG00000143799 PARP1 ENSG00000153234 NR4A2 H. sapiens SDL Slorth 0.948161 View
ENSG00000065029 ZNF76 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.94816 View
ENSG00000079999 KEAP1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.948107 View
ENSG00000143799 PARP1 ENSG00000151729 SLC25A4 H. sapiens SSL Slorth 0.948031 View
ENSG00000143799 PARP1 ENSG00000166483 WEE1 H. sapiens SDL Slorth 0.948024 View
ENSG00000143799 PARP1 ENSG00000159692 CTBP1 H. sapiens SDL Slorth 0.94798 View
ENSG00000143799 PARP1 ENSG00000164754 RAD21 H. sapiens SDL Slorth 0.947957 View
ENSG00000073921 PICALM ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.947948 View