PARP1

ENSG00000143799 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0003910 DNA ligase (ATP) activity
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0030331 estrogen receptor binding
GO:0042802 identical protein binding
GO:0042826 histone deacetylase binding
GO:0047485 protein N-terminus binding
GO:0051287 NAD binding
GO:0070412 R-SMAD binding

Drugs

Drug name Description
OLAPARIB PARP 1, 2 & 3 inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
Parp D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000143799 PARP1 ENSG00000166670 MMP10 H. sapiens SDL Slorth 0.951827 View
ENSG00000088808 PPP1R13B ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.951818 View
ENSG00000143799 PARP1 ENSG00000156508 EEF1A1 H. sapiens SSL Slorth 0.951796 View
ENSG00000143799 PARP1 ENSG00000165637 VDAC2 H. sapiens SSL Slorth 0.95179 View
ENSG00000118985 ELL2 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.951748 View
ENSG00000143799 PARP1 ENSG00000149136 SSRP1 H. sapiens SSL Slorth 0.951741 View
ENSG00000143799 PARP1 ENSG00000185122 HSF1 H. sapiens SDL Slorth 0.951735 View
ENSG00000143799 PARP1 ENSG00000168283 BMI1 H. sapiens SDL Slorth 0.951723 View
ENSG00000143799 PARP1 ENSG00000157456 CCNB2 H. sapiens SSL Slorth 0.951469 View
ENSG00000143799 PARP1 ENSG00000164934 DCAF13 H. sapiens SSL Slorth 0.95142 View
ENSG00000073111 MCM2 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.951401 View
ENSG00000143799 PARP1 ENSG00000162775 RBM15 H. sapiens SDL Slorth 0.951376 View
ENSG00000143799 PARP1 ENSG00000188603 CLN3 H. sapiens SDL Slorth 0.951248 View
ENSG00000140443 IGF1R ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.951057 View
ENSG00000070950 RAD18 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.95104 View
ENSG00000143799 PARP1 ENSG00000167985 SDHAF2 H. sapiens SDL Slorth 0.951038 View
ENSG00000143799 PARP1 ENSG00000177189 RPS6KA3 H. sapiens SSL Slorth 0.951027 View
ENSG00000143799 PARP1 ENSG00000164362 TERT H. sapiens SSL Slorth 0.951026 View
ENSG00000136628 EPRS ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.950883 View
ENSG00000143799 PARP1 ENSG00000197275 RAD54B H. sapiens SDL Slorth 0.95082 View
ENSG00000136273 HUS1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.950667 View
ENSG00000143799 PARP1 ENSG00000185651 UBE2L3 H. sapiens SSL Slorth 0.950639 View
ENSG00000118046 STK11 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.950472 View
ENSG00000114423 CBLB ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.950429 View
ENSG00000143799 PARP1 ENSG00000198791 CNOT7 H. sapiens SDL Slorth 0.950353 View
ENSG00000114166 KAT2B ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.950337 View
ENSG00000122406 RPL5 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.95031 View
ENSG00000143799 PARP1 ENSG00000185104 FAF1 H. sapiens SSL Slorth 0.950306 View
ENSG00000105612 DNASE2 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.950296 View
ENSG00000143799 PARP1 ENSG00000175216 CKAP5 H. sapiens SDL Slorth 0.950215 View
ENSG00000143799 PARP1 ENSG00000153147 SMARCA5 H. sapiens SSL Slorth 0.950178 View
ENSG00000143799 PARP1 ENSG00000154016 GRAP H. sapiens SDL Slorth 0.950099 View
ENSG00000121022 COPS5 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.950022 View
ENSG00000143799 PARP1 ENSG00000175054 ATR H. sapiens SSL Slorth 0.950021 View
ENSG00000143799 PARP1 ENSG00000168439 STIP1 H. sapiens SSL Slorth 0.949991 View
ENSG00000143799 PARP1 ENSG00000213585 VDAC1 H. sapiens SDL Slorth 0.949923 View
ENSG00000143799 PARP1 ENSG00000177889 UBE2N H. sapiens SSL Slorth 0.949881 View
ENSG00000143799 PARP1 ENSG00000221823 PPP3R1 H. sapiens SSL Slorth 0.949799 View
ENSG00000044574 HSPA5 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.949719 View
ENSG00000143799 PARP1 ENSG00000145604 SKP2 H. sapiens SSL Slorth 0.949718 View