PICALM - PARP1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PICALM	ENSG00000073921	T-ALL AML	No drugs in record	protein binding 1-phosphatidylinositol binding clathrin binding clathrin heavy chain binding clathrin adaptor activity cadherin binding involved in cell-cell adhesion	YAP1801 (S. cerevisiae) YAP1802 (S. cerevisiae) unc-11 (C. elegans) lap (D. melanogaster)
PARP1	ENSG00000143799	No diseases in record	OLAPARIB	DNA binding DNA ligase (ATP) activity NAD+ ADP-ribosyltransferase activity protein binding transcription factor binding zinc ion binding enzyme binding protein kinase binding estrogen receptor binding identical protein binding histone deacetylase binding protein N-terminus binding NAD binding R-SMAD binding	Parp (D. melanogaster)