PARP1

ENSG00000143799 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0003910 DNA ligase (ATP) activity
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0030331 estrogen receptor binding
GO:0042802 identical protein binding
GO:0042826 histone deacetylase binding
GO:0047485 protein N-terminus binding
GO:0051287 NAD binding
GO:0070412 R-SMAD binding

Drugs

Drug name Description
OLAPARIB PARP 1, 2 & 3 inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
Parp D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000143799 PARP1 ENSG00000161956 SENP3 H. sapiens SSL Slorth 0.94103 View
ENSG00000143799 PARP1 ENSG00000185236 RAB11B H. sapiens SDL Slorth 0.941023 View
ENSG00000143799 PARP1 ENSG00000163399 ATP1A1 H. sapiens SSL Slorth 0.94101 View
ENSG00000143799 PARP1 ENSG00000165025 SYK H. sapiens SSL Slorth 0.941005 View
ENSG00000143799 PARP1 ENSG00000175766 EIF4E1B H. sapiens SDL Slorth 0.94099 View
ENSG00000143799 PARP1 ENSG00000175334 BANF1 H. sapiens SSL Slorth 0.940965 View
ENSG00000100297 MCM5 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.940923 View
ENSG00000078043 PIAS2 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.940909 View
ENSG00000143799 PARP1 ENSG00000169189 NSMCE1 H. sapiens SSL Slorth 0.940857 View
ENSG00000143799 PARP1 ENSG00000172175 MALT1 H. sapiens SDL Slorth 0.940797 View
ENSG00000143799 PARP1 ENSG00000175054 ATR H. sapiens SDL Slorth 0.940737 View
ENSG00000100503 NIN ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.940676 View
ENSG00000085840 ORC1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.940623 View
ENSG00000005156 LIG3 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.940539 View
ENSG00000143799 PARP1 ENSG00000240771 ARHGEF25 H. sapiens SDL Slorth 0.940507 View
ENSG00000143799 PARP1 ENSG00000182255 KCNA4 H. sapiens SDL Slorth 0.940485 View
ENSG00000143799 PARP1 ENSG00000198400 NTRK1 H. sapiens SSL Slorth 0.940461 View
ENSG00000143799 PARP1 ENSG00000205339 IPO7 H. sapiens SSL Slorth 0.940388 View
ENSG00000143799 PARP1 ENSG00000173933 RBM4 H. sapiens SDL Slorth 0.94034 View
ENSG00000143799 PARP1 ENSG00000253729 PRKDC H. sapiens SSL Slorth 0.939995 View
ENSG00000143799 PARP1 ENSG00000197111 PCBP2 H. sapiens SDL Slorth 0.939987 View
ENSG00000143799 PARP1 ENSG00000169083 AR H. sapiens SDL Slorth 0.939907 View
ENSG00000131196 NFATC1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.939818 View
ENSG00000132155 RAF1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.939744 View
ENSG00000143799 PARP1 ENSG00000185345 PARK2 H. sapiens SSL Slorth 0.939722 View
ENSG00000108424 KPNB1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.939665 View
ENSG00000143799 PARP1 ENSG00000159720 ATP6V0D1 H. sapiens SDL Slorth 0.939657 View
ENSG00000143799 PARP1 ENSG00000197323 TRIM33 H. sapiens SDL Slorth 0.939639 View
ENSG00000143799 PARP1 ENSG00000171148 TADA3 H. sapiens SDL Slorth 0.939482 View
ENSG00000143799 PARP1 ENSG00000165699 TSC1 H. sapiens SSL Slorth 0.939397 View
ENSG00000097007 ABL1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.939097 View
ENSG00000047315 POLR2B ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.939091 View
ENSG00000143799 PARP1 ENSG00000162231 NXF1 H. sapiens SSL Slorth 0.939066 View
ENSG00000143799 PARP1 ENSG00000204843 DCTN1 H. sapiens SDL Slorth 0.939058 View
ENSG00000143799 PARP1 ENSG00000159210 SNF8 H. sapiens SDL Slorth 0.938925 View
ENSG00000143799 PARP1 ENSG00000198887 SMC5 H. sapiens SSL Slorth 0.938712 View
ENSG00000143799 PARP1 ENSG00000176974 SHMT1 H. sapiens SSL Slorth 0.938694 View
ENSG00000078304 PPP2R5C ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.938562 View
ENSG00000078747 ITCH ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.938506 View
ENSG00000143799 PARP1 ENSG00000154997 SEPT14 H. sapiens SDL Slorth 0.938423 View