PARP1

ENSG00000143799 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0003910 DNA ligase (ATP) activity
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0030331 estrogen receptor binding
GO:0042802 identical protein binding
GO:0042826 histone deacetylase binding
GO:0047485 protein N-terminus binding
GO:0051287 NAD binding
GO:0070412 R-SMAD binding

Drugs

Drug name Description
OLAPARIB PARP 1, 2 & 3 inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
Parp D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000112592 TBP ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.938253 View
ENSG00000089250 NOS1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.938155 View
ENSG00000143799 PARP1 ENSG00000173933 RBM4 H. sapiens SSL Slorth 0.938117 View
ENSG00000143799 PARP1 ENSG00000183955 KMT5A H. sapiens SSL Slorth 0.938089 View
ENSG00000143799 PARP1 ENSG00000167461 RAB8A H. sapiens SDL Slorth 0.938052 View
ENSG00000100030 MAPK1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.938028 View
ENSG00000085224 ATRX ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.937975 View
ENSG00000143799 PARP1 ENSG00000182199 SHMT2 H. sapiens SSL Slorth 0.937969 View
ENSG00000143799 PARP1 ENSG00000198522 GPN1 H. sapiens SSL Slorth 0.937944 View
ENSG00000109971 HSPA8 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.937732 View
ENSG00000143799 PARP1 ENSG00000196591 HDAC2 H. sapiens SSL Slorth 0.937627 View
ENSG00000143799 PARP1 ENSG00000162302 RPS6KA4 H. sapiens SSL Slorth 0.937603 View
ENSG00000143799 PARP1 ENSG00000243678 NME2 H. sapiens SDL Slorth 0.937562 View
ENSG00000143799 PARP1 ENSG00000196296 ATP2A1 H. sapiens SDL Slorth 0.937384 View
ENSG00000143799 PARP1 ENSG00000178999 AURKB H. sapiens SSL Slorth 0.937355 View
ENSG00000087470 DNM1L ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.937329 View
ENSG00000143799 PARP1 ENSG00000144134 RABL2A H. sapiens SDL Slorth 0.937318 View
ENSG00000143799 PARP1 ENSG00000175197 DDIT3 H. sapiens SDL Slorth 0.93729 View
ENSG00000131747 TOP2A ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.93728 View
ENSG00000143799 PARP1 ENSG00000197451 HNRNPAB H. sapiens SSL Slorth 0.937239 View
ENSG00000143799 PARP1 ENSG00000183741 CBX6 H. sapiens SDL Slorth 0.937157 View
ENSG00000143799 PARP1 ENSG00000163840 DTX3L H. sapiens SDL Slorth 0.937156 View
ENSG00000143799 PARP1 ENSG00000148737 TCF7L2 H. sapiens SDL Slorth 0.937062 View
ENSG00000132646 PCNA ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.937048 View
ENSG00000143799 PARP1 ENSG00000149782 PLCB3 H. sapiens SDL Slorth 0.936999 View
ENSG00000080986 NDC80 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.936963 View
ENSG00000143799 PARP1 ENSG00000172175 MALT1 H. sapiens SSL Slorth 0.936764 View
ENSG00000143799 PARP1 ENSG00000173846 PLK3 H. sapiens SSL Slorth 0.93676 View
ENSG00000125450 NUP85 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.936712 View
ENSG00000128512 DOCK4 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.936672 View
ENSG00000124784 RIOK1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.936672 View
ENSG00000143799 PARP1 ENSG00000148660 CAMK2G H. sapiens SSL Slorth 0.936619 View
ENSG00000131437 KIF3A ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.936544 View
ENSG00000143799 PARP1 ENSG00000162909 CAPN2 H. sapiens SSL Slorth 0.936523 View
ENSG00000143799 PARP1 ENSG00000164885 CDK5 H. sapiens SSL Slorth 0.936369 View
ENSG00000060069 CTDP1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.936044 View
ENSG00000143799 PARP1 ENSG00000177606 JUN H. sapiens SSL Slorth 0.935952 View
ENSG00000114166 KAT2B ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.935909 View
ENSG00000143799 PARP1 ENSG00000166855 CLPX H. sapiens SSL Slorth 0.935896 View
ENSG00000143799 PARP1 ENSG00000144554 FANCD2 H. sapiens SSL Slorth 0.935823 View