IGF1R

ENSG00000140443 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0005010 insulin-like growth factor-activated receptor activity
GO:0005158 insulin receptor binding
GO:0005515 protein binding
GO:0005520 insulin-like growth factor binding
GO:0005524 ATP binding
GO:0031994 insulin-like growth factor I binding
GO:0042802 identical protein binding
GO:0043548 phosphatidylinositol 3-kinase binding
GO:0043559 insulin binding
GO:0043560 insulin receptor substrate binding

Drugs

Drug name Description
MECASERMIN Insulin-like growth factor I receptor agonist
MECASERMIN RINFABATE Insulin-like growth factor I receptor agonist

Diseases

No diseases in record

Orthologs

Gene Organism
daf-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000115221 ITGB6 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.937241 View
ENSG00000140443 IGF1R ENSG00000183207 RUVBL2 H. sapiens SSL Slorth 0.937088 View
ENSG00000140443 IGF1R ENSG00000183791 TCEB3C H. sapiens SDL Slorth 0.936995 View
ENSG00000089159 PXN ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.936981 View
ENSG00000006451 RALA ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.936837 View
ENSG00000061273 HDAC7 ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.936793 View
ENSG00000140443 IGF1R ENSG00000240771 ARHGEF25 H. sapiens SDL Slorth 0.936665 View
ENSG00000001626 CFTR ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.936637 View
ENSG00000105810 CDK6 ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.936512 View
ENSG00000129354 AP1M2 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.936308 View
ENSG00000102683 SGCG ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.936182 View
ENSG00000090372 STRN4 ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.935787 View
ENSG00000089159 PXN ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.935608 View
ENSG00000112679 DUSP22 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.935465 View
ENSG00000140443 IGF1R ENSG00000183684 ALYREF H. sapiens SSL Slorth 0.934554 View
ENSG00000137845 ADAM10 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.934525 View
ENSG00000140443 IGF1R ENSG00000157764 BRAF H. sapiens SSL Slorth 0.934321 View
ENSG00000080986 NDC80 ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.934169 View
ENSG00000140443 IGF1R ENSG00000171150 SOCS5 H. sapiens SDL Slorth 0.933915 View
ENSG00000115808 STRN ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.933882 View
ENSG00000130561 SAG ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.933643 View
ENSG00000137073 UBAP2 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.933643 View
ENSG00000100982 PCIF1 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.933643 View
ENSG00000066468 FGFR2 ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.933623 View
ENSG00000072163 LIMS2 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.933591 View
ENSG00000140443 IGF1R ENSG00000198838 RYR3 H. sapiens SDL Slorth 0.933587 View
ENSG00000010017 RANBP9 ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.933564 View
ENSG00000137486 ARRB1 ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.933401 View
ENSG00000140443 IGF1R ENSG00000154237 LRRK1 H. sapiens SDL Slorth 0.933169 View
ENSG00000134982 APC ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.9331 View
ENSG00000138829 FBN2 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.932856 View
ENSG00000063660 GPC1 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.932821 View
ENSG00000117399 CDC20 ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.932544 View
ENSG00000114554 PLXNA1 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.932504 View
ENSG00000108424 KPNB1 ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.932272 View
ENSG00000140443 IGF1R ENSG00000167085 PHB H. sapiens SSL Slorth 0.932154 View
ENSG00000128052 KDR ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.932064 View
ENSG00000140199 SLC12A6 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.931986 View
ENSG00000085511 MAP3K4 ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.931892 View
ENSG00000128908 INO80 ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.931892 View