IGF1R

ENSG00000140443 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0005010 insulin-like growth factor-activated receptor activity
GO:0005158 insulin receptor binding
GO:0005515 protein binding
GO:0005520 insulin-like growth factor binding
GO:0005524 ATP binding
GO:0031994 insulin-like growth factor I binding
GO:0042802 identical protein binding
GO:0043548 phosphatidylinositol 3-kinase binding
GO:0043559 insulin binding
GO:0043560 insulin receptor substrate binding

Drugs

Drug name Description
MECASERMIN Insulin-like growth factor I receptor agonist
MECASERMIN RINFABATE Insulin-like growth factor I receptor agonist

Diseases

No diseases in record

Orthologs

Gene Organism
daf-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000140443 IGF1R ENSG00000169252 ADRB2 H. sapiens SDL Slorth 0.943647 View
ENSG00000135604 STX11 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.943206 View
ENSG00000088367 EPB41L1 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.942938 View
ENSG00000067606 PRKCZ ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.942836 View
ENSG00000121774 KHDRBS1 ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.942813 View
ENSG00000124486 USP9X ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.942531 View
ENSG00000140443 IGF1R ENSG00000196419 XRCC6 H. sapiens SSL Slorth 0.942415 View
ENSG00000140443 IGF1R ENSG00000141968 VAV1 H. sapiens SSL Slorth 0.942256 View
ENSG00000134308 YWHAQ ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.942203 View
ENSG00000132155 RAF1 ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.941991 View
ENSG00000012048 BRCA1 ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.941755 View
ENSG00000140443 IGF1R ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.941747 View
ENSG00000105287 PRKD2 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.941419 View
ENSG00000140443 IGF1R ENSG00000143033 MTF2 H. sapiens SDL Slorth 0.941332 View
ENSG00000140443 IGF1R ENSG00000157168 NRG1 H. sapiens SDL Slorth 0.941231 View
ENSG00000124181 PLCG1 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.941036 View
ENSG00000075785 RAB7A ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.941004 View
ENSG00000140443 IGF1R ENSG00000154229 PRKCA H. sapiens SSL Slorth 0.940855 View
ENSG00000140443 IGF1R ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.940414 View
ENSG00000140443 IGF1R ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.940349 View
ENSG00000106346 USP42 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.940329 View
ENSG00000132386 SERPINF1 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.9403 View
ENSG00000085832 EPS15 ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.940212 View
ENSG00000140443 IGF1R ENSG00000160224 AIRE H. sapiens SDL Slorth 0.940115 View
ENSG00000111262 KCNA1 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.939744 View
ENSG00000021574 SPAST ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.939658 View
ENSG00000067141 NEO1 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.939401 View
ENSG00000140443 IGF1R ENSG00000141510 TP53 H. sapiens SDL Slorth 0.939323 View
ENSG00000067560 RHOA ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.939318 View
ENSG00000140443 IGF1R ENSG00000165731 RET H. sapiens SDL Slorth 0.939286 View
ENSG00000026103 FAS ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.93857 View
ENSG00000135312 HTR1B ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.93854 View
ENSG00000140443 IGF1R ENSG00000181163 NPM1 H. sapiens SSL Slorth 0.938533 View
ENSG00000061918 GUCY1B3 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.938459 View
ENSG00000130703 OSBPL2 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.938058 View
ENSG00000077380 DYNC1I2 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.938058 View
ENSG00000067829 IDH3G ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.938027 View
ENSG00000117400 MPL ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.937746 View
ENSG00000134871 COL4A2 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.937705 View
ENSG00000140443 IGF1R ENSG00000150093 ITGB1 H. sapiens SDL Slorth 0.937402 View