IGF1R

ENSG00000140443 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0005010 insulin-like growth factor-activated receptor activity
GO:0005158 insulin receptor binding
GO:0005515 protein binding
GO:0005520 insulin-like growth factor binding
GO:0005524 ATP binding
GO:0031994 insulin-like growth factor I binding
GO:0042802 identical protein binding
GO:0043548 phosphatidylinositol 3-kinase binding
GO:0043559 insulin binding
GO:0043560 insulin receptor substrate binding

Drugs

Drug name Description
MECASERMIN Insulin-like growth factor I receptor agonist
MECASERMIN RINFABATE Insulin-like growth factor I receptor agonist

Diseases

No diseases in record

Orthologs

Gene Organism
daf-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000113721 PDGFRB ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.968856 View
ENSG00000082898 XPO1 ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.968689 View
ENSG00000136807 CDK9 ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.968018 View
ENSG00000140443 IGF1R ENSG00000175376 EIF1AD H. sapiens SDL Slorth 0.967507 View
ENSG00000080815 PSEN1 ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.967408 View
ENSG00000105974 CAV1 ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.967073 View
ENSG00000140443 IGF1R ENSG00000160145 KALRN H. sapiens SDL Slorth 0.965762 View
ENSG00000078747 ITCH ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.965412 View
ENSG00000101146 RAE1 ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.964132 View
ENSG00000134086 VHL ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.964001 View
ENSG00000138376 BARD1 ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.96394 View
ENSG00000140443 IGF1R ENSG00000157601 MX1 H. sapiens SDL Slorth 0.963394 View
ENSG00000112118 MCM3 ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.962574 View
ENSG00000140443 IGF1R ENSG00000185896 LAMP1 H. sapiens SDL Slorth 0.962562 View
ENSG00000004700 RECQL ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.961949 View
ENSG00000101266 CSNK2A1 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.961891 View
ENSG00000121879 PIK3CA ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.961798 View
ENSG00000132646 PCNA ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.961355 View
ENSG00000140443 IGF1R ENSG00000169862 CTNND2 H. sapiens SDL Slorth 0.96114 View
ENSG00000118046 STK11 ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.960795 View
ENSG00000136238 RAC1 ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.960515 View
ENSG00000109906 ZBTB16 ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.960363 View
ENSG00000140443 IGF1R ENSG00000206181 TCEB3B H. sapiens SDL Slorth 0.960231 View
ENSG00000140443 IGF1R ENSG00000142208 AKT1 H. sapiens SDL Slorth 0.960168 View
ENSG00000140443 IGF1R ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.960156 View
ENSG00000140443 IGF1R ENSG00000162889 MAPKAPK2 H. sapiens SDL Slorth 0.959932 View
ENSG00000140443 IGF1R ENSG00000152601 MBNL1 H. sapiens SDL Slorth 0.959729 View
ENSG00000140443 IGF1R ENSG00000256223 ZNF10 H. sapiens SDL Slorth 0.958881 View
ENSG00000140443 IGF1R ENSG00000143420 ENSA H. sapiens SDL Slorth 0.958827 View
ENSG00000140443 IGF1R ENSG00000141448 GATA6 H. sapiens SDL Slorth 0.95881 View
ENSG00000100372 SLC25A17 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.958752 View
ENSG00000102996 MMP15 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.958675 View
ENSG00000082701 GSK3B ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.958461 View
ENSG00000140443 IGF1R ENSG00000144668 ITGA9 H. sapiens SDL Slorth 0.958396 View
ENSG00000109971 HSPA8 ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.958328 View
ENSG00000111540 RAB5B ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.958171 View
ENSG00000080815 PSEN1 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.957764 View
ENSG00000140443 IGF1R ENSG00000169926 KLF13 H. sapiens SDL Slorth 0.95773 View
ENSG00000140443 IGF1R ENSG00000143801 PSEN2 H. sapiens SDL Slorth 0.957497 View
ENSG00000140443 IGF1R ENSG00000205629 LCMT1 H. sapiens SDL Slorth 0.957179 View