PDGFRB - IGF1R

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PDGFRB	ENSG00000113721	MPN AML CMML CML	BECAPLERMIN DASATINIB IMATINIB NINTEDANIB PAZOPANIB REGORAFENIB SORAFENIB SUNITINIB	protein tyrosine kinase activity platelet activating factor receptor activity platelet-derived growth factor-activated receptor activity platelet-derived growth factor beta-receptor activity Ras guanyl-nucleotide exchange factor activity receptor binding platelet-derived growth factor receptor binding protein binding ATP binding enzyme binding protein kinase binding vascular endothelial growth factor binding phosphatidylinositol 3-kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity platelet-derived growth factor binding	Pvr (D. melanogaster)
IGF1R	ENSG00000140443	No diseases in record	MECASERMIN MECASERMIN RINFABATE	protein tyrosine kinase activity insulin-like growth factor-activated receptor activity insulin receptor binding protein binding insulin-like growth factor binding ATP binding insulin-like growth factor I binding identical protein binding phosphatidylinositol 3-kinase binding insulin binding insulin receptor substrate binding	daf-2 (C. elegans)