Go term | Description |
---|---|
GO:0001042 | RNA polymerase I core binding |
GO:0004713 | protein tyrosine kinase activity |
GO:0004714 | transmembrane receptor protein tyrosine kinase activity |
GO:0004716 | signal transducer, downstream of receptor, with protein tyrosine kinase activity |
GO:0004888 | transmembrane signaling receptor activity |
GO:0005088 | Ras guanyl-nucleotide exchange factor activity |
GO:0005515 | protein binding |
GO:0005524 | ATP binding |
GO:0008022 | protein C-terminus binding |
GO:0019903 | protein phosphatase binding |
GO:0042802 | identical protein binding |
GO:0043125 | ErbB-3 class receptor binding |
GO:0046934 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity |
GO:0046982 | protein heterodimerization activity |
GO:0046983 | protein dimerization activity |
GO:0019838 | growth factor binding |
Drug name | Description |
---|---|
AFATINIB | Epidermal growth factor receptor erbB1 inhibitor |
LAPATINIB | Epidermal growth factor receptor erbB1 inhibitor |
PERTUZUMAB | Receptor protein-tyrosine kinase erbB-2 inhibitor |
TRASTUZUMAB | Receptor protein-tyrosine kinase erbB-2 inhibitor |
TRASTUZUMAB EMTANSINE | Tubulin inhibitor |
VANDETANIB | Epidermal growth factor receptor inhibitor |
Disease Name |
---|
breast |
ovarian |
other tumour types |
NSCLC |
gastric |
Gene | Organism | |
---|---|---|
let-23 | C. elegans | |
Egfr | D. melanogaster |
Gene ID A | Gene Name A | Gene ID B | Gene Symbol B | Organism | Source | Score? | ||
---|---|---|---|---|---|---|---|---|
ENSG00000141736 | ERBB2 | ENSG00000196923 | PDLIM7 | H. sapiens | SDL | Slorth | 0.934799 | View |
ENSG00000141736 | ERBB2 | ENSG00000165806 | CASP7 | H. sapiens | SDL | Slorth | 0.934771 | View |
ENSG00000141736 | ERBB2 | ENSG00000162775 | RBM15 | H. sapiens | SDL | Slorth | 0.934718 | View |
ENSG00000067606 | PRKCZ | ENSG00000141736 | ERBB2 | H. sapiens | SSL | Slorth | 0.934646 | View |
ENSG00000137825 | ITPKA | ENSG00000141736 | ERBB2 | H. sapiens | SDL | Slorth | 0.934597 | View |
ENSG00000141736 | ERBB2 | ENSG00000147316 | MCPH1 | H. sapiens | SDL | Slorth | 0.934509 | View |
ENSG00000141736 | ERBB2 | ENSG00000163399 | ATP1A1 | H. sapiens | SSL | Slorth | 0.934443 | View |
ENSG00000078114 | NEBL | ENSG00000141736 | ERBB2 | H. sapiens | SDL | Slorth | 0.934434 | View |
ENSG00000141736 | ERBB2 | ENSG00000198793 | MTOR | H. sapiens | SDL | Slorth | 0.934397 | View |
ENSG00000141736 | ERBB2 | ENSG00000196839 | ADA | H. sapiens | SSL | Slorth | 0.934211 | View |
ENSG00000141543 | EIF4A3 | ENSG00000141736 | ERBB2 | H. sapiens | SSL | Slorth | 0.934174 | View |
ENSG00000080986 | NDC80 | ENSG00000141736 | ERBB2 | H. sapiens | SSL | Slorth | 0.934135 | View |
ENSG00000141736 | ERBB2 | ENSG00000161800 | RACGAP1 | H. sapiens | SDL | Slorth | 0.93411 | View |
ENSG00000141736 | ERBB2 | ENSG00000161956 | SENP3 | H. sapiens | SSL | Slorth | 0.9341 | View |
ENSG00000141736 | ERBB2 | ENSG00000164077 | MON1A | H. sapiens | SDL | Slorth | 0.934074 | View |
ENSG00000141736 | ERBB2 | ENSG00000197579 | TOPORS | H. sapiens | SSL | Slorth | 0.933889 | View |
ENSG00000141736 | ERBB2 | ENSG00000181449 | SOX2 | H. sapiens | SDL | Slorth | 0.93372 | View |
ENSG00000141736 | ERBB2 | ENSG00000163558 | PRKCI | H. sapiens | SSL | Slorth | 0.933703 | View |
ENSG00000141736 | ERBB2 | ENSG00000198909 | MAP3K3 | H. sapiens | SSL | Slorth | 0.933692 | View |
ENSG00000141736 | ERBB2 | ENSG00000149273 | RPS3 | H. sapiens | SDL | Slorth | 0.933645 | View |
ENSG00000141736 | ERBB2 | ENSG00000169967 | MAP3K2 | H. sapiens | SSL | Slorth | 0.933604 | View |
ENSG00000141736 | ERBB2 | ENSG00000169100 | SLC25A6 | H. sapiens | SSL | Slorth | 0.933583 | View |
ENSG00000141736 | ERBB2 | ENSG00000152104 | PTPN14 | H. sapiens | SSL | Slorth | 0.933509 | View |
ENSG00000114867 | EIF4G1 | ENSG00000141736 | ERBB2 | H. sapiens | SSL | Slorth | 0.933494 | View |
ENSG00000141736 | ERBB2 | ENSG00000188906 | LRRK2 | H. sapiens | SDL | Slorth | 0.933483 | View |
ENSG00000141736 | ERBB2 | ENSG00000173757 | STAT5B | H. sapiens | SDL | Slorth | 0.933061 | View |
ENSG00000072062 | PRKACA | ENSG00000141736 | ERBB2 | H. sapiens | SSL | Slorth | 0.933006 | View |
ENSG00000105568 | PPP2R1A | ENSG00000141736 | ERBB2 | H. sapiens | SSL | Slorth | 0.932994 | View |
ENSG00000141736 | ERBB2 | ENSG00000153147 | SMARCA5 | H. sapiens | SSL | Slorth | 0.932952 | View |
ENSG00000135341 | MAP3K7 | ENSG00000141736 | ERBB2 | H. sapiens | SDL | Slorth | 0.93291 | View |
ENSG00000141736 | ERBB2 | ENSG00000160691 | SHC1 | H. sapiens | SSL | Slorth | 0.932901 | View |
ENSG00000141736 | ERBB2 | ENSG00000178568 | ERBB4 | H. sapiens | SDL | Slorth | 0.932894 | View |
ENSG00000116478 | HDAC1 | ENSG00000141736 | ERBB2 | H. sapiens | SSL | Slorth | 0.932892 | View |
ENSG00000141736 | ERBB2 | ENSG00000160867 | FGFR4 | H. sapiens | SDL | Slorth | 0.932875 | View |
ENSG00000141736 | ERBB2 | ENSG00000156508 | EEF1A1 | H. sapiens | SDL | Slorth | 0.932801 | View |
ENSG00000141736 | ERBB2 | ENSG00000158169 | FANCC | H. sapiens | SDL | Slorth | 0.93279 | View |
ENSG00000141736 | ERBB2 | ENSG00000165684 | SNAPC4 | H. sapiens | SDL | Slorth | 0.932769 | View |
ENSG00000087995 | METTL2A | ENSG00000141736 | ERBB2 | H. sapiens | SDL | Slorth | 0.932706 | View |
ENSG00000100906 | NFKBIA | ENSG00000141736 | ERBB2 | H. sapiens | SDL | Slorth | 0.932535 | View |
ENSG00000117222 | RBBP5 | ENSG00000141736 | ERBB2 | H. sapiens | SSL | Slorth | 0.932402 | View |