TYMS

ENSG00000176890 - H. sapiens

Pathways

Go term Description
GO:0000166 nucleotide binding
GO:0003729 mRNA binding
GO:0004799 thymidylate synthase activity
GO:0005542 folic acid binding
GO:0008144 drug binding
GO:0042803 protein homodimerization activity
GO:0048037 cofactor binding

Drugs

Drug name Description
CAPECITABINE Thymidylate synthase inhibitor
FLOXURIDINE Thymidylate synthase inhibitor
FLUOROURACIL Thymidylate synthase inhibitor
GEMCITABINE
PEMETREXED Dihydrofolate reductase inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
CDC21 S. cerevisiae
Ts D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000078140 UBE2K ENSG00000176890 TYMS H. sapiens SSL Slorth 0.869862 View
ENSG00000135446 CDK4 ENSG00000176890 TYMS H. sapiens SSL Slorth 0.869314 View
ENSG00000115524 SF3B1 ENSG00000176890 TYMS H. sapiens SSL Slorth 0.868517 View
ENSG00000157764 BRAF ENSG00000176890 TYMS H. sapiens SSL Slorth 0.868483 View
ENSG00000130726 TRIM28 ENSG00000176890 TYMS H. sapiens SSL Slorth 0.868391 View
ENSG00000165392 WRN ENSG00000176890 TYMS H. sapiens SSL Slorth 0.868135 View
ENSG00000148400 NOTCH1 ENSG00000176890 TYMS H. sapiens SSL Slorth 0.865637 View
ENSG00000069869 NEDD4 ENSG00000176890 TYMS H. sapiens SSL Slorth 0.864913 View
ENSG00000113721 PDGFRB ENSG00000176890 TYMS H. sapiens SSL Slorth 0.863685 View
ENSG00000150753 CCT5 ENSG00000176890 TYMS H. sapiens SSL Slorth 0.862657 View
ENSG00000145386 CCNA2 ENSG00000176890 TYMS H. sapiens SSL Slorth 0.86197 View
ENSG00000103126 AXIN1 ENSG00000176890 TYMS H. sapiens SSL Slorth 0.860531 View
ENSG00000101966 XIAP ENSG00000176890 TYMS H. sapiens SSL Slorth 0.859413 View
ENSG00000280548 FBL ENSG00000176890 TYMS H. sapiens SSL Slorth 0.858823 View
ENSG00000130939 UBE4B ENSG00000176890 TYMS H. sapiens SSL Slorth 0.857015 View
ENSG00000141543 EIF4A3 ENSG00000176890 TYMS H. sapiens SSL Slorth 0.856019 View
ENSG00000170365 SMAD1 ENSG00000176890 TYMS H. sapiens SSL Slorth 0.855488 View
ENSG00000169750 RAC3 ENSG00000176890 TYMS H. sapiens SSL Slorth 0.855434 View
ENSG00000117676 RPS6KA1 ENSG00000176890 TYMS H. sapiens SSL Slorth 0.855373 View
ENSG00000100387 RBX1 ENSG00000176890 TYMS H. sapiens SSL Slorth 0.854807 View
ENSG00000154229 PRKCA ENSG00000176890 TYMS H. sapiens SSL Slorth 0.854614 View
ENSG00000093009 CDC45 ENSG00000176890 TYMS H. sapiens SSL Slorth 0.852603 View
ENSG00000132170 PPARG ENSG00000176890 TYMS H. sapiens SSL Slorth 0.851309 View
ENSG00000110107 PRPF19 ENSG00000176890 TYMS H. sapiens SSL Slorth 0.851223 View
ENSG00000092201 SUPT16H ENSG00000176890 TYMS H. sapiens SSL Slorth 0.850772 View
ENSG00000136937 NCBP1 ENSG00000176890 TYMS H. sapiens SSL Slorth 0.85074 View
ENSG00000102978 POLR2C ENSG00000176890 TYMS H. sapiens SSL Slorth 0.850301 View
ENSG00000166913 YWHAB ENSG00000176890 TYMS H. sapiens SSL Slorth 0.849663 View
ENSG00000100644 HIF1A ENSG00000176890 TYMS H. sapiens SSL Slorth 0.849465 View
ENSG00000114062 UBE3A ENSG00000176890 TYMS H. sapiens SSL Slorth 0.849153 View
ENSG00000168148 HIST3H3 ENSG00000176890 TYMS H. sapiens SSL Slorth 0.847843 View
ENSG00000136518 ACTL6A ENSG00000176890 TYMS H. sapiens SSL Slorth 0.847282 View
ENSG00000134308 YWHAQ ENSG00000176890 TYMS H. sapiens SSL Slorth 0.844493 View
ENSG00000108424 KPNB1 ENSG00000176890 TYMS H. sapiens SSL Slorth 0.843792 View
ENSG00000131508 UBE2D2 ENSG00000176890 TYMS H. sapiens SSL Slorth 0.843207 View
ENSG00000142192 APP ENSG00000176890 TYMS H. sapiens SSL Slorth 0.842903 View
ENSG00000104738 MCM4 ENSG00000176890 TYMS H. sapiens SSL Slorth 0.841894 View
ENSG00000137693 YAP1 ENSG00000176890 TYMS H. sapiens SSL Slorth 0.841681 View
ENSG00000135018 UBQLN1 ENSG00000176890 TYMS H. sapiens SSL Slorth 0.84155 View
ENSG00000067560 RHOA ENSG00000176890 TYMS H. sapiens SSL Slorth 0.841482 View