LIG4

ENSG00000174405 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0003909 DNA ligase activity
GO:0003910 DNA ligase (ATP) activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0016874 ligase activity
GO:0046872 metal ion binding

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
DNL4 S. cerevisiae
lig-4 C. elegans
Lig4 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000112592 TBP ENSG00000174405 LIG4 H. sapiens SSL Slorth 0.934074 View
ENSG00000131747 TOP2A ENSG00000174405 LIG4 H. sapiens SDL Slorth 0.933994 View
ENSG00000097007 ABL1 ENSG00000174405 LIG4 H. sapiens SSL Slorth 0.933054 View
ENSG00000114391 RPL24 ENSG00000174405 LIG4 H. sapiens SDL Slorth 0.931943 View
ENSG00000122026 RPL21 ENSG00000174405 LIG4 H. sapiens SDL Slorth 0.93194 View
ENSG00000171791 BCL2 ENSG00000174405 LIG4 H. sapiens SSL Slorth 0.931564 View
ENSG00000146648 EGFR ENSG00000174405 LIG4 H. sapiens SSL Slorth 0.931328 View
ENSG00000110395 CBL ENSG00000174405 LIG4 H. sapiens SDL Slorth 0.930983 View
ENSG00000141027 NCOR1 ENSG00000174405 LIG4 H. sapiens SSL Slorth 0.92962 View
ENSG00000174231 PRPF8 ENSG00000174405 LIG4 H. sapiens SDL Slorth 0.929291 View
ENSG00000072401 UBE2D1 ENSG00000174405 LIG4 H. sapiens SSL Slorth 0.928968 View
ENSG00000010810 FYN ENSG00000174405 LIG4 H. sapiens SSL Slorth 0.927796 View
ENSG00000132383 RPA1 ENSG00000174405 LIG4 H. sapiens SSL Slorth 0.927243 View
ENSG00000132155 RAF1 ENSG00000174405 LIG4 H. sapiens SSL Slorth 0.925716 View
ENSG00000082701 GSK3B ENSG00000174405 LIG4 H. sapiens SSL Slorth 0.925689 View
ENSG00000101146 RAE1 ENSG00000174405 LIG4 H. sapiens SSL Slorth 0.925466 View
ENSG00000051180 RAD51 ENSG00000174405 LIG4 H. sapiens SDL Slorth 0.925041 View
ENSG00000004700 RECQL ENSG00000174405 LIG4 H. sapiens SSL Slorth 0.925035 View
ENSG00000112062 MAPK14 ENSG00000174405 LIG4 H. sapiens SSL Slorth 0.92474 View
ENSG00000116251 RPL22 ENSG00000174405 LIG4 H. sapiens SDL Slorth 0.923728 View
ENSG00000141646 SMAD4 ENSG00000174405 LIG4 H. sapiens SSL Slorth 0.922824 View
ENSG00000105372 RPS19 ENSG00000174405 LIG4 H. sapiens SDL Slorth 0.921889 View
ENSG00000168283 BMI1 ENSG00000174405 LIG4 H. sapiens SDL Slorth 0.919989 View
ENSG00000174405 LIG4 ENSG00000177885 GRB2 H. sapiens SDL Slorth 0.919828 View
ENSG00000124181 PLCG1 ENSG00000174405 LIG4 H. sapiens SSL Slorth 0.919268 View
ENSG00000149554 CHEK1 ENSG00000174405 LIG4 H. sapiens SDL Slorth 0.918317 View
ENSG00000104365 IKBKB ENSG00000174405 LIG4 H. sapiens SSL Slorth 0.918033 View
ENSG00000174405 LIG4 ENSG00000221983 UBA52 H. sapiens SDL Slorth 0.917601 View
ENSG00000132646 PCNA ENSG00000174405 LIG4 H. sapiens SSL Slorth 0.916779 View
ENSG00000164305 CASP3 ENSG00000174405 LIG4 H. sapiens SSL Slorth 0.916674 View
ENSG00000170315 UBB ENSG00000174405 LIG4 H. sapiens SSL Slorth 0.91629 View
ENSG00000168610 STAT3 ENSG00000174405 LIG4 H. sapiens SSL Slorth 0.915218 View
ENSG00000140988 RPS2 ENSG00000174405 LIG4 H. sapiens SDL Slorth 0.914877 View
ENSG00000149554 CHEK1 ENSG00000174405 LIG4 H. sapiens SSL Slorth 0.914792 View
ENSG00000150991 UBC ENSG00000174405 LIG4 H. sapiens SDL Slorth 0.913951 View
ENSG00000077097 TOP2B ENSG00000174405 LIG4 H. sapiens SDL Slorth 0.91372 View
ENSG00000096717 SIRT1 ENSG00000174405 LIG4 H. sapiens SSL Slorth 0.913548 View
ENSG00000121022 COPS5 ENSG00000174405 LIG4 H. sapiens SSL Slorth 0.913385 View
ENSG00000101412 E2F1 ENSG00000174405 LIG4 H. sapiens SSL Slorth 0.912567 View
ENSG00000095002 MSH2 ENSG00000174405 LIG4 H. sapiens SDL Slorth 0.912341 View