TOP2B - LIG4

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
TOP2B ENSG00000077097

No diseases in record

ETOPOSIDE
TENIPOSIDE
chromatin binding
DNA topoisomerase type II (ATP-hydrolyzing) activity
protein kinase C binding
ATP binding
protein C-terminus binding
DNA binding, bending
enzyme binding
histone deacetylase binding
metal ion binding
protein heterodimerization activity
TOP2 (S. cerevisiae)
cin-4 (C. elegans)
top-2 (C. elegans)
LIG4 ENSG00000174405

No diseases in record

No drugs in record

DNA binding
DNA ligase activity
DNA ligase (ATP) activity
protein binding
ATP binding
protein C-terminus binding
ligase activity
metal ion binding
DNL4 (S. cerevisiae)
lig-4 (C. elegans)
Lig4 (D. melanogaster)