SMAD3

ENSG00000166949 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific
GO:0000987 core promoter proximal region sequence-specific DNA binding
GO:0001102 RNA polymerase II activating transcription factor binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0005160 transforming growth factor beta receptor binding
GO:0005515 protein binding
GO:0005518 collagen binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019901 protein kinase binding
GO:0019902 phosphatase binding
GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
GO:0031490 chromatin DNA binding
GO:0031625 ubiquitin protein ligase binding
GO:0035326 enhancer binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043130 ubiquitin binding
GO:0043425 bHLH transcription factor binding
GO:0043565 sequence-specific DNA binding
GO:0044212 transcription regulatory region DNA binding
GO:0046982 protein heterodimerization activity
GO:0070410 co-SMAD binding
GO:0070412 R-SMAD binding
GO:0000988 transcription factor activity, protein binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal carcinoma
oral squamous cell carcinoma

Orthologs

Gene Organism
sma-3 C. elegans
sma-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000143093 STRIP1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.918165 View
ENSG00000166949 SMAD3 ENSG00000183741 CBX6 H. sapiens SDL Slorth 0.918 View
ENSG00000087258 GNAO1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.917956 View
ENSG00000105976 MET ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.917837 View
ENSG00000076555 ACACB ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.917802 View
ENSG00000156304 SCAF4 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.917799 View
ENSG00000123374 CDK2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.91775 View
ENSG00000166949 SMAD3 ENSG00000187741 FANCA H. sapiens SSL Slorth 0.917711 View
ENSG00000101460 MAP1LC3A ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.917571 View
ENSG00000156482 RPL30 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.917564 View
ENSG00000160868 CYP3A4 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.917531 View
ENSG00000166949 SMAD3 ENSG00000213741 RPS29 H. sapiens SDL Slorth 0.91746 View
ENSG00000108953 YWHAE ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.917428 View
ENSG00000136143 SUCLA2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.917352 View
ENSG00000166949 SMAD3 ENSG00000178896 EXOSC4 H. sapiens SSL Slorth 0.917287 View
ENSG00000157020 SEC13 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.917221 View
ENSG00000163083 INHBB ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.917085 View
ENSG00000077522 ACTN2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.916785 View
ENSG00000111602 TIMELESS ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.916764 View
ENSG00000145782 ATG12 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.916724 View
ENSG00000136827 TOR1A ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.916713 View
ENSG00000078140 UBE2K ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.91671 View
ENSG00000139726 DENR ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.91664 View
ENSG00000050820 BCAR1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.916637 View
ENSG00000166949 SMAD3 ENSG00000204209 DAXX H. sapiens SDL Slorth 0.916605 View
ENSG00000089157 RPLP0 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.916577 View
ENSG00000084774 CAD ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.916483 View
ENSG00000166949 SMAD3 ENSG00000261832 RP11-435I10.4 H. sapiens SDL Slorth 0.91646 View
ENSG00000166949 SMAD3 ENSG00000169744 LDB2 H. sapiens SSL Slorth 0.916404 View
ENSG00000096968 JAK2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.916285 View
ENSG00000166949 SMAD3 ENSG00000171720 HDAC3 H. sapiens SDL Slorth 0.916282 View
ENSG00000084764 MAPRE3 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.916191 View
ENSG00000129084 PSMA1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.916057 View
ENSG00000134308 YWHAQ ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.916031 View
ENSG00000153140 CETN3 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.915928 View
ENSG00000164885 CDK5 ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.915861 View
ENSG00000159720 ATP6V0D1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.915806 View
ENSG00000148341 SH3GLB2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.915775 View
ENSG00000035403 VCL ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.915736 View
ENSG00000091009 RBM27 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.91565 View