SMAD3

ENSG00000166949 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific
GO:0000987 core promoter proximal region sequence-specific DNA binding
GO:0001102 RNA polymerase II activating transcription factor binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0005160 transforming growth factor beta receptor binding
GO:0005515 protein binding
GO:0005518 collagen binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019901 protein kinase binding
GO:0019902 phosphatase binding
GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
GO:0031490 chromatin DNA binding
GO:0031625 ubiquitin protein ligase binding
GO:0035326 enhancer binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043130 ubiquitin binding
GO:0043425 bHLH transcription factor binding
GO:0043565 sequence-specific DNA binding
GO:0044212 transcription regulatory region DNA binding
GO:0046982 protein heterodimerization activity
GO:0070410 co-SMAD binding
GO:0070412 R-SMAD binding
GO:0000988 transcription factor activity, protein binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal carcinoma
oral squamous cell carcinoma

Orthologs

Gene Organism
sma-3 C. elegans
sma-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000128513 POT1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.912621 View
ENSG00000159461 AMFR ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.91256 View
ENSG00000129559 NEDD8 ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.912533 View
ENSG00000157227 MMP14 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.912468 View
ENSG00000166949 SMAD3 ENSG00000196781 TLE1 H. sapiens SDL Slorth 0.912388 View
ENSG00000073111 MCM2 ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.912346 View
ENSG00000051108 HERPUD1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.912321 View
ENSG00000166949 SMAD3 ENSG00000178950 GAK H. sapiens SSL Slorth 0.912275 View
ENSG00000157911 PEX10 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.912055 View
ENSG00000134982 APC ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.912054 View
ENSG00000114302 PRKAR2A ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.912019 View
ENSG00000132155 RAF1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.911821 View
ENSG00000166949 SMAD3 ENSG00000183207 RUVBL2 H. sapiens SSL Slorth 0.911746 View
ENSG00000166949 SMAD3 ENSG00000198791 CNOT7 H. sapiens SSL Slorth 0.911724 View
ENSG00000111450 STX2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.911522 View
ENSG00000037042 TUBG2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.911372 View
ENSG00000166949 SMAD3 ENSG00000175792 RUVBL1 H. sapiens SSL Slorth 0.911291 View
ENSG00000166949 SMAD3 ENSG00000197728 RPS26 H. sapiens SDL Slorth 0.911155 View
ENSG00000144935 TRPC1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.910991 View
ENSG00000166949 SMAD3 ENSG00000198959 TGM2 H. sapiens SSL Slorth 0.910966 View
ENSG00000147669 POLR2K ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.910872 View
ENSG00000166949 SMAD3 ENSG00000167323 STIM1 H. sapiens SDL Slorth 0.910767 View
ENSG00000110107 PRPF19 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.910494 View
ENSG00000141384 TAF4B ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.910451 View
ENSG00000166949 SMAD3 ENSG00000198056 PRIM1 H. sapiens SSL Slorth 0.910407 View
ENSG00000153147 SMARCA5 ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.910334 View
ENSG00000107819 SFXN3 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.910327 View
ENSG00000166949 SMAD3 ENSG00000196396 PTPN1 H. sapiens SSL Slorth 0.910234 View
ENSG00000102882 MAPK3 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.909938 View
ENSG00000091106 NLRC4 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.909865 View
ENSG00000077348 EXOSC5 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.909852 View
ENSG00000166949 SMAD3 ENSG00000169249 ZRSR2 H. sapiens SDL Slorth 0.9097 View
ENSG00000112096 SOD2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.909418 View
ENSG00000166949 SMAD3 ENSG00000171843 MLLT3 H. sapiens SSL Slorth 0.909402 View
ENSG00000021826 CPS1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.909197 View
ENSG00000143437 ARNT ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.909184 View
ENSG00000100644 HIF1A ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.909108 View
ENSG00000161057 PSMC2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.908986 View
ENSG00000111276 CDKN1B ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.908975 View
ENSG00000166949 SMAD3 ENSG00000185345 PARK2 H. sapiens SSL Slorth 0.908899 View