SMAD3

ENSG00000166949 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific
GO:0000987 core promoter proximal region sequence-specific DNA binding
GO:0001102 RNA polymerase II activating transcription factor binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0005160 transforming growth factor beta receptor binding
GO:0005515 protein binding
GO:0005518 collagen binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019901 protein kinase binding
GO:0019902 phosphatase binding
GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
GO:0031490 chromatin DNA binding
GO:0031625 ubiquitin protein ligase binding
GO:0035326 enhancer binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043130 ubiquitin binding
GO:0043425 bHLH transcription factor binding
GO:0043565 sequence-specific DNA binding
GO:0044212 transcription regulatory region DNA binding
GO:0046982 protein heterodimerization activity
GO:0070410 co-SMAD binding
GO:0070412 R-SMAD binding
GO:0000988 transcription factor activity, protein binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal carcinoma
oral squamous cell carcinoma

Orthologs

Gene Organism
sma-3 C. elegans
sma-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000163932 PRKCD ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.920326 View
ENSG00000126561 STAT5A ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.9202 View
ENSG00000058056 USP13 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.920141 View
ENSG00000112186 CAP2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.920114 View
ENSG00000119392 GLE1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.920029 View
ENSG00000166226 CCT2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.920011 View
ENSG00000076356 PLXNA2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.920006 View
ENSG00000166949 SMAD3 ENSG00000176444 CLK2 H. sapiens SSL Slorth 0.919945 View
ENSG00000166949 SMAD3 ENSG00000175518 UBQLNL H. sapiens SDL Slorth 0.91989 View
ENSG00000166949 SMAD3 ENSG00000260914 RP11-343C2.11 H. sapiens SDL Slorth 0.91989 View
ENSG00000136854 STXBP1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.919888 View
ENSG00000057294 PKP2 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.919818 View
ENSG00000127914 AKAP9 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.919697 View
ENSG00000078674 PCM1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.919661 View
ENSG00000105173 CCNE1 ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.919532 View
ENSG00000090565 RAB11FIP3 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.919495 View
ENSG00000166200 COPS2 ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.919367 View
ENSG00000137486 ARRB1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.91936 View
ENSG00000108384 RAD51C ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.919274 View
ENSG00000166949 SMAD3 ENSG00000197535 MYO5A H. sapiens SDL Slorth 0.919193 View
ENSG00000131236 CAP1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.919113 View
ENSG00000071564 TCF3 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.919074 View
ENSG00000166949 SMAD3 ENSG00000185532 PRKG1 H. sapiens SSL Slorth 0.919066 View
ENSG00000113594 LIFR ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.919025 View
ENSG00000121481 RNF2 ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.918901 View
ENSG00000142534 RPS11 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.918858 View
ENSG00000112039 FANCE ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.918784 View
ENSG00000136631 VPS45 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.918698 View
ENSG00000164885 CDK5 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.918688 View
ENSG00000074201 CLNS1A ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.91863 View
ENSG00000166949 SMAD3 ENSG00000176105 YES1 H. sapiens SSL Slorth 0.918559 View
ENSG00000166949 SMAD3 ENSG00000172409 CLP1 H. sapiens SDL Slorth 0.918536 View
ENSG00000166949 SMAD3 ENSG00000183161 FANCF H. sapiens SSL Slorth 0.918524 View
ENSG00000119912 IDE ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.91847 View
ENSG00000109062 SLC9A3R1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.918434 View
ENSG00000079387 SENP1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.91839 View
ENSG00000150753 CCT5 ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.918363 View
ENSG00000118260 CREB1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.918329 View
ENSG00000103197 TSC2 ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.918306 View
ENSG00000097007 ABL1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.918221 View