ERCC2

ENSG00000104884 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0008094 DNA-dependent ATPase activity
GO:0043139 5'-3' DNA helicase activity
GO:0046872 metal ion binding
GO:0047485 protein N-terminus binding
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0004672 protein kinase activity
GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity

Drugs

No drugs in record

Diseases

Disease Name
skin basal cell
skin squamous cell
melanoma

Orthologs

Gene Organism
RAD3 S. cerevisiae
Y50D7A.11 C. elegans
Xpd D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000072062 PRKACA ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.902297 View
ENSG00000100201 DDX17 ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.901906 View
ENSG00000089157 RPLP0 ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.901783 View
ENSG00000104884 ERCC2 ENSG00000169813 HNRNPF H. sapiens SDL Slorth 0.901361 View
ENSG00000080815 PSEN1 ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.901344 View
ENSG00000064012 CASP8 ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.901118 View
ENSG00000104884 ERCC2 ENSG00000159216 RUNX1 H. sapiens SDL Slorth 0.901074 View
ENSG00000104884 ERCC2 ENSG00000134057 CCNB1 H. sapiens SDL Slorth 0.901041 View
ENSG00000093009 CDC45 ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.900373 View
ENSG00000036257 CUL3 ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.894614 View
ENSG00000010810 FYN ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.893517 View
ENSG00000103194 USP10 ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.890176 View
ENSG00000100906 NFKBIA ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.88953 View
ENSG00000099804 CDC34 ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.886938 View
ENSG00000023445 BIRC3 ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.886663 View
ENSG00000102978 POLR2C ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.886192 View
ENSG00000061938 TNK2 ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.886016 View
ENSG00000005007 UPF1 ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.885765 View
ENSG00000096968 JAK2 ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.885731 View
ENSG00000085840 ORC1 ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.884644 View
ENSG00000099817 POLR2E ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.884109 View
ENSG00000103126 AXIN1 ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.88308 View
ENSG00000100644 HIF1A ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.874725 View
ENSG00000080824 HSP90AA1 ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.873117 View
ENSG00000047315 POLR2B ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.865904 View
ENSG00000070831 CDC42 ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.86542 View
ENSG00000080503 SMARCA2 ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.862895 View
ENSG00000094916 CBX5 ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.860107 View
ENSG00000063244 U2AF2 ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.859896 View
ENSG00000103479 RBL2 ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.850181 View
ENSG00000049759 NEDD4L ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.847278 View
ENSG00000073584 SMARCE1 ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.84348 View
ENSG00000072518 MARK2 ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.843056 View
ENSG00000104884 ERCC2 ENSG00000154229 PRKCA H. sapiens SSL Slorth 0.838623 View
ENSG00000104695 PPP2CB ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.83662 View
ENSG00000104884 ERCC2 ENSG00000134086 VHL H. sapiens SSL Slorth 0.836197 View
ENSG00000067560 RHOA ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.835707 View
ENSG00000103197 TSC2 ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.834788 View
ENSG00000001626 CFTR ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.833832 View
ENSG00000095002 MSH2 ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.828802 View