PSEN1 - ERCC2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PSEN1	ENSG00000080815	No diseases in record	No drugs in record	endopeptidase activity aspartic-type endopeptidase activity calcium channel activity protein binding beta-catenin binding PDZ domain binding cadherin binding	sel-12 (C. elegans)
ERCC2	ENSG00000104884	skin basal cell skin squamous cell melanoma	No drugs in record	DNA binding ATP-dependent DNA helicase activity protein binding ATP binding protein C-terminus binding DNA-dependent ATPase activity 5'-3' DNA helicase activity metal ion binding protein N-terminus binding 4 iron, 4 sulfur cluster binding protein kinase activity RNA polymerase II carboxy-terminal domain kinase activity	RAD3 (S. cerevisiae) Y50D7A.11 (C. elegans) Xpd (D. melanogaster)