ERCC2

ENSG00000104884 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0008094 DNA-dependent ATPase activity
GO:0043139 5'-3' DNA helicase activity
GO:0046872 metal ion binding
GO:0047485 protein N-terminus binding
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0004672 protein kinase activity
GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity

Drugs

No drugs in record

Diseases

Disease Name
skin basal cell
skin squamous cell
melanoma

Orthologs

Gene Organism
RAD3 S. cerevisiae
Y50D7A.11 C. elegans
Xpd D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000070950 RAD18 ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.911528 View
ENSG00000104884 ERCC2 ENSG00000132383 RPA1 H. sapiens SDL Slorth 0.911157 View
ENSG00000102882 MAPK3 ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.911055 View
ENSG00000104884 ERCC2 ENSG00000140988 RPS2 H. sapiens SDL Slorth 0.910851 View
ENSG00000104884 ERCC2 ENSG00000115738 ID2 H. sapiens SDL Slorth 0.910726 View
ENSG00000104884 ERCC2 ENSG00000157933 SKI H. sapiens SDL Slorth 0.910545 View
ENSG00000096384 HSP90AB1 ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.910372 View
ENSG00000104884 ERCC2 ENSG00000181163 NPM1 H. sapiens SDL Slorth 0.91022 View
ENSG00000036257 CUL3 ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.910164 View
ENSG00000069869 NEDD4 ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.910046 View
ENSG00000104884 ERCC2 ENSG00000136450 SRSF1 H. sapiens SDL Slorth 0.909788 View
ENSG00000104884 ERCC2 ENSG00000124782 RREB1 H. sapiens SDL Slorth 0.909056 View
ENSG00000104884 ERCC2 ENSG00000114030 KPNA1 H. sapiens SDL Slorth 0.908778 View
ENSG00000104884 ERCC2 ENSG00000189067 LITAF H. sapiens SDL Slorth 0.908508 View
ENSG00000089159 PXN ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.908123 View
ENSG00000104884 ERCC2 ENSG00000118046 STK11 H. sapiens SDL Slorth 0.90801 View
ENSG00000104884 ERCC2 ENSG00000213923 CSNK1E H. sapiens SDL Slorth 0.907999 View
ENSG00000104738 MCM4 ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.907975 View
ENSG00000104884 ERCC2 ENSG00000176720 BOK H. sapiens SDL Slorth 0.907766 View
ENSG00000104884 ERCC2 ENSG00000122406 RPL5 H. sapiens SDL Slorth 0.907227 View
ENSG00000104884 ERCC2 ENSG00000106546 AHR H. sapiens SDL Slorth 0.907194 View
ENSG00000104884 ERCC2 ENSG00000117676 RPS6KA1 H. sapiens SDL Slorth 0.906541 View
ENSG00000104884 ERCC2 ENSG00000152601 MBNL1 H. sapiens SDL Slorth 0.906083 View
ENSG00000104884 ERCC2 ENSG00000130177 CDC16 H. sapiens SDL Slorth 0.905992 View
ENSG00000104884 ERCC2 ENSG00000126368 NR1D1 H. sapiens SDL Slorth 0.90594 View
ENSG00000104884 ERCC2 ENSG00000132341 RAN H. sapiens SDL Slorth 0.905911 View
ENSG00000058729 RIOK2 ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.905812 View
ENSG00000102054 RBBP7 ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.905594 View
ENSG00000104884 ERCC2 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.905449 View
ENSG00000102054 RBBP7 ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.90494 View
ENSG00000104884 ERCC2 ENSG00000134954 ETS1 H. sapiens SDL Slorth 0.904424 View
ENSG00000104884 ERCC2 ENSG00000178999 AURKB H. sapiens SDL Slorth 0.904383 View
ENSG00000072310 SREBF1 ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.903972 View
ENSG00000104884 ERCC2 ENSG00000119335 SET H. sapiens SDL Slorth 0.903872 View
ENSG00000078747 ITCH ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.903869 View
ENSG00000095002 MSH2 ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.903569 View
ENSG00000104884 ERCC2 ENSG00000145386 CCNA2 H. sapiens SDL Slorth 0.903381 View
ENSG00000100462 PRMT5 ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.903148 View
ENSG00000101665 SMAD7 ENSG00000104884 ERCC2 H. sapiens SSL Slorth 0.902979 View
ENSG00000104884 ERCC2 ENSG00000198911 SREBF2 H. sapiens SDL Slorth 0.9027 View