ERCC2 - RAF1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ERCC2	ENSG00000104884	skin basal cell skin squamous cell melanoma	No drugs in record	DNA binding ATP-dependent DNA helicase activity protein binding ATP binding protein C-terminus binding DNA-dependent ATPase activity 5'-3' DNA helicase activity metal ion binding protein N-terminus binding 4 iron, 4 sulfur cluster binding protein kinase activity RNA polymerase II carboxy-terminal domain kinase activity	RAD3 (S. cerevisiae) Y50D7A.11 (C. elegans) Xpd (D. melanogaster)
RAF1	ENSG00000132155	pilocytic astrocytoma prostate	REGORAFENIB SORAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity protein binding ATP binding kinase activity enzyme binding mitogen-activated protein kinase kinase binding identical protein binding metal ion binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)