ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000104388 RAB2A H. sapiens SSL Slorth 0.859255 View
ENSG00000091831 ESR1 ENSG00000205981 DNAJC19 H. sapiens SSL Slorth 0.859146 View
ENSG00000091831 ESR1 ENSG00000164171 ITGA2 H. sapiens SSL Slorth 0.859119 View
ENSG00000091831 ESR1 ENSG00000106367 AP1S1 H. sapiens SSL Slorth 0.85907 View
ENSG00000091831 ESR1 ENSG00000132470 ITGB4 H. sapiens SSL Slorth 0.859027 View
ENSG00000091831 ESR1 ENSG00000184979 USP18 H. sapiens SSL Slorth 0.858962 View
ENSG00000091831 ESR1 ENSG00000173039 RELA H. sapiens SSL Slorth 0.858897 View
ENSG00000091831 ESR1 ENSG00000117020 AKT3 H. sapiens SSL Slorth 0.858837 View
ENSG00000091831 ESR1 ENSG00000108106 UBE2S H. sapiens SSL Slorth 0.858835 View
ENSG00000091831 ESR1 ENSG00000177879 AP3S1 H. sapiens SSL Slorth 0.858812 View
ENSG00000091831 ESR1 ENSG00000114127 XRN1 H. sapiens SSL Slorth 0.858685 View
ENSG00000091831 ESR1 ENSG00000160271 RALGDS H. sapiens SSL Slorth 0.858585 View
ENSG00000091831 ESR1 ENSG00000107954 NEURL1 H. sapiens SSL Slorth 0.858571 View
ENSG00000091831 ESR1 ENSG00000136997 MYC H. sapiens SSL Slorth 0.858531 View
ENSG00000091831 ESR1 ENSG00000137054 POLR1E H. sapiens SSL Slorth 0.858427 View
ENSG00000091831 ESR1 ENSG00000111640 GAPDH H. sapiens SSL Slorth 0.858399 View
ENSG00000091831 ESR1 ENSG00000102030 NAA10 H. sapiens SSL Slorth 0.858274 View
ENSG00000091831 ESR1 ENSG00000118260 CREB1 H. sapiens SSL Slorth 0.858241 View
ENSG00000091831 ESR1 ENSG00000135144 DTX1 H. sapiens SSL Slorth 0.858141 View
ENSG00000091831 ESR1 ENSG00000134352 IL6ST H. sapiens SSL Slorth 0.858077 View
ENSG00000091831 ESR1 ENSG00000101361 NOP56 H. sapiens SSL Slorth 0.858069 View
ENSG00000091831 ESR1 ENSG00000228425 VPS52 H. sapiens SSL Slorth 0.858031 View
ENSG00000091831 ESR1 ENSG00000175220 ARHGAP1 H. sapiens SSL Slorth 0.858027 View
ENSG00000091831 ESR1 ENSG00000136381 IREB2 H. sapiens SSL Slorth 0.858018 View
ENSG00000091831 ESR1 ENSG00000101146 RAE1 H. sapiens SSL Slorth 0.857961 View
ENSG00000091831 ESR1 ENSG00000099901 RANBP1 H. sapiens SSL Slorth 0.857874 View
ENSG00000091831 ESR1 ENSG00000151422 FER H. sapiens SSL Slorth 0.857857 View
ENSG00000091831 ESR1 ENSG00000149269 PAK1 H. sapiens SSL Slorth 0.857816 View
ENSG00000091831 ESR1 ENSG00000204843 DCTN1 H. sapiens SSL Slorth 0.857767 View
ENSG00000091831 ESR1 ENSG00000196591 HDAC2 H. sapiens SSL Slorth 0.857379 View
ENSG00000091831 ESR1 ENSG00000140678 ITGAX H. sapiens SSL Slorth 0.857322 View
ENSG00000091831 ESR1 ENSG00000242247 ARFGAP3 H. sapiens SSL Slorth 0.85729 View
ENSG00000091831 ESR1 ENSG00000153071 DAB2 H. sapiens SSL Slorth 0.857255 View
ENSG00000091831 ESR1 ENSG00000117318 ID3 H. sapiens SSL Slorth 0.857231 View
ENSG00000091831 ESR1 ENSG00000101255 TRIB3 H. sapiens SSL Slorth 0.857203 View
ENSG00000091831 ESR1 ENSG00000146872 TLK2 H. sapiens SSL Slorth 0.857139 View
ENSG00000091831 ESR1 ENSG00000142892 PIGK H. sapiens SSL Slorth 0.857087 View
ENSG00000091831 ESR1 ENSG00000162337 LRP5 H. sapiens SSL Slorth 0.856965 View
ENSG00000091831 ESR1 ENSG00000173933 RBM4 H. sapiens SSL Slorth 0.856934 View
ENSG00000091831 ESR1 ENSG00000130956 HABP4 H. sapiens SSL Slorth 0.856914 View