ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000178209 PLEC H. sapiens SSL Slorth 0.862776 View
ENSG00000091831 ESR1 ENSG00000156587 UBE2L6 H. sapiens SSL Slorth 0.862675 View
ENSG00000091831 ESR1 ENSG00000186432 KPNA4 H. sapiens SSL Slorth 0.86247 View
ENSG00000091831 ESR1 ENSG00000107341 UBE2R2 H. sapiens SSL Slorth 0.862378 View
ENSG00000091831 ESR1 ENSG00000177613 CSTF2T H. sapiens SSL Slorth 0.862356 View
ENSG00000091831 ESR1 ENSG00000119541 VPS4B H. sapiens SSL Slorth 0.862351 View
ENSG00000091831 ESR1 ENSG00000172936 MYD88 H. sapiens SSL Slorth 0.862282 View
ENSG00000091831 ESR1 ENSG00000105443 CYTH2 H. sapiens SSL Slorth 0.862154 View
ENSG00000091831 ESR1 ENSG00000156709 AIFM1 H. sapiens SSL Slorth 0.862118 View
ENSG00000091831 ESR1 ENSG00000196914 ARHGEF12 H. sapiens SSL Slorth 0.861992 View
ENSG00000091831 ESR1 ENSG00000104964 AES H. sapiens SSL Slorth 0.86199 View
ENSG00000091831 ESR1 ENSG00000138794 CASP6 H. sapiens SSL Slorth 0.861877 View
ENSG00000091831 ESR1 ENSG00000127948 POR H. sapiens SSL Slorth 0.861817 View
ENSG00000091831 ESR1 ENSG00000147536 GINS4 H. sapiens SSL Slorth 0.86178 View
ENSG00000091831 ESR1 ENSG00000198804 MT-CO1 H. sapiens SSL Slorth 0.861778 View
ENSG00000091831 ESR1 ENSG00000204388 HSPA1B H. sapiens SSL Slorth 0.861505 View
ENSG00000091831 ESR1 ENSG00000182255 KCNA4 H. sapiens SSL Slorth 0.861416 View
ENSG00000091831 ESR1 ENSG00000167004 PDIA3 H. sapiens SSL Slorth 0.861262 View
ENSG00000091831 ESR1 ENSG00000198431 TXNRD1 H. sapiens SSL Slorth 0.861172 View
ENSG00000091831 ESR1 ENSG00000128591 FLNC H. sapiens SSL Slorth 0.861149 View
ENSG00000091831 ESR1 ENSG00000159200 RCAN1 H. sapiens SSL Slorth 0.860966 View
ENSG00000091831 ESR1 ENSG00000182872 RBM10 H. sapiens SSL Slorth 0.860881 View
ENSG00000091831 ESR1 ENSG00000105963 ADAP1 H. sapiens SSL Slorth 0.860859 View
ENSG00000091831 ESR1 ENSG00000141027 NCOR1 H. sapiens SSL Slorth 0.860639 View
ENSG00000091831 ESR1 ENSG00000115073 ACTR1B H. sapiens SSL Slorth 0.860548 View
ENSG00000091831 ESR1 ENSG00000138795 LEF1 H. sapiens SSL Slorth 0.860411 View
ENSG00000091831 ESR1 ENSG00000156299 TIAM1 H. sapiens SSL Slorth 0.860348 View
ENSG00000091831 ESR1 ENSG00000128595 CALU H. sapiens SSL Slorth 0.86031 View
ENSG00000091831 ESR1 ENSG00000133318 RTN3 H. sapiens SSL Slorth 0.860292 View
ENSG00000091831 ESR1 ENSG00000133316 WDR74 H. sapiens SSL Slorth 0.860249 View
ENSG00000091831 ESR1 ENSG00000120948 TARDBP H. sapiens SSL Slorth 0.860155 View
ENSG00000091831 ESR1 ENSG00000137497 NUMA1 H. sapiens SSL Slorth 0.859988 View
ENSG00000091831 ESR1 ENSG00000205339 IPO7 H. sapiens SSL Slorth 0.859974 View
ENSG00000091831 ESR1 ENSG00000151276 MAGI1 H. sapiens SSL Slorth 0.859845 View
ENSG00000091831 ESR1 ENSG00000172340 SUCLG2 H. sapiens SSL Slorth 0.859827 View
ENSG00000091831 ESR1 ENSG00000128607 KLHDC10 H. sapiens SSL Slorth 0.859652 View
ENSG00000091831 ESR1 ENSG00000165684 SNAPC4 H. sapiens SSL Slorth 0.85957 View
ENSG00000091831 ESR1 ENSG00000170296 GABARAP H. sapiens SSL Slorth 0.859495 View
ENSG00000091831 ESR1 ENSG00000115041 KCNIP3 H. sapiens SSL Slorth 0.859481 View
ENSG00000091831 ESR1 ENSG00000154016 GRAP H. sapiens SSL Slorth 0.859378 View