ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000197063 MAFG H. sapiens SDL Slorth 0.935213 View
ENSG00000091831 ESR1 ENSG00000198467 TPM2 H. sapiens SDL Slorth 0.935203 View
ENSG00000091831 ESR1 ENSG00000092529 CAPN3 H. sapiens SSL Slorth 0.935147 View
ENSG00000091831 ESR1 ENSG00000168066 SF1 H. sapiens SSL Slorth 0.935131 View
ENSG00000091831 ESR1 ENSG00000104738 MCM4 H. sapiens SSL Slorth 0.935123 View
ENSG00000091831 ESR1 ENSG00000096384 HSP90AB1 H. sapiens SDL Slorth 0.935102 View
ENSG00000091831 ESR1 ENSG00000169139 UBE2V2 H. sapiens SSL Slorth 0.934944 View
ENSG00000091831 ESR1 ENSG00000170144 HNRNPA3 H. sapiens SDL Slorth 0.93489 View
ENSG00000091831 ESR1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.934877 View
ENSG00000091831 ESR1 ENSG00000105011 ASF1B H. sapiens SSL Slorth 0.934775 View
ENSG00000091831 ESR1 ENSG00000120616 EPC1 H. sapiens SDL Slorth 0.934767 View
ENSG00000091831 ESR1 ENSG00000147010 SH3KBP1 H. sapiens SSL Slorth 0.934636 View
ENSG00000091831 ESR1 ENSG00000183791 TCEB3C H. sapiens SDL Slorth 0.934636 View
ENSG00000091831 ESR1 ENSG00000099797 TECR H. sapiens SDL Slorth 0.934603 View
ENSG00000091831 ESR1 ENSG00000140307 GTF2A2 H. sapiens SDL Slorth 0.93458 View
ENSG00000091831 ESR1 ENSG00000115073 ACTR1B H. sapiens SDL Slorth 0.934507 View
ENSG00000091831 ESR1 ENSG00000115085 ZAP70 H. sapiens SSL Slorth 0.934475 View
ENSG00000091831 ESR1 ENSG00000135521 LTV1 H. sapiens SSL Slorth 0.934405 View
ENSG00000091831 ESR1 ENSG00000130939 UBE4B H. sapiens SSL Slorth 0.934337 View
ENSG00000091831 ESR1 ENSG00000112249 ASCC3 H. sapiens SSL Slorth 0.934301 View
ENSG00000091831 ESR1 ENSG00000177565 TBL1XR1 H. sapiens SSL Slorth 0.934224 View
ENSG00000091831 ESR1 ENSG00000113721 PDGFRB H. sapiens SSL Slorth 0.934067 View
ENSG00000091831 ESR1 ENSG00000164944 KIAA1429 H. sapiens SDL Slorth 0.934037 View
ENSG00000091831 ESR1 ENSG00000139718 SETD1B H. sapiens SSL Slorth 0.934033 View
ENSG00000091831 ESR1 ENSG00000115053 NCL H. sapiens SDL Slorth 0.933968 View
ENSG00000091831 ESR1 ENSG00000097046 CDC7 H. sapiens SSL Slorth 0.933925 View
ENSG00000091831 ESR1 ENSG00000136238 RAC1 H. sapiens SDL Slorth 0.933812 View
ENSG00000091831 ESR1 ENSG00000198612 COPS8 H. sapiens SSL Slorth 0.933797 View
ENSG00000091831 ESR1 ENSG00000118513 MYB H. sapiens SSL Slorth 0.93378 View
ENSG00000091831 ESR1 ENSG00000183431 SF3A3 H. sapiens SDL Slorth 0.933772 View
ENSG00000091831 ESR1 ENSG00000173327 MAP3K11 H. sapiens SSL Slorth 0.933757 View
ENSG00000091831 ESR1 ENSG00000112294 ALDH5A1 H. sapiens SDL Slorth 0.933747 View
ENSG00000091831 ESR1 ENSG00000113643 RARS H. sapiens SSL Slorth 0.933745 View
ENSG00000091831 ESR1 ENSG00000160803 UBQLN4 H. sapiens SSL Slorth 0.933739 View
ENSG00000078142 PIK3C3 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.933655 View
ENSG00000091831 ESR1 ENSG00000123908 AGO2 H. sapiens SSL Slorth 0.933523 View
ENSG00000091831 ESR1 ENSG00000123737 EXOSC9 H. sapiens SSL Slorth 0.93351 View
ENSG00000091831 ESR1 ENSG00000163029 SMC6 H. sapiens SSL Slorth 0.933388 View
ENSG00000091831 ESR1 ENSG00000092847 AGO1 H. sapiens SSL Slorth 0.933329 View
ENSG00000091831 ESR1 ENSG00000177283 FZD8 H. sapiens SDL Slorth 0.933316 View