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Genes
Gene:
Organism:
H. sapiens
S. cerevisiae
S. pombe
D. melanogaster
C. elegans
Type:
SSL
SDL
Quality:
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Experimentally Validated
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Cancer gene:
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Druggable:
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Gene
Ensembl ID
Organism
Diseases
Drugs
Ontology
Interactions
GOLT1B
ENSG00000111711
H. sapiens
signal transducer activity
...
76
GON4L
ENSG00000116580
H. sapiens
DNA binding
transcription corepressor activity
...
1
GPI
ENSG00000105220
H. sapiens
glucose-6-phosphate isomerase activity
glucose-6-phosphate isomerase activity
cytokine activity
...
55
GPN3
ENSG00000111231
H. sapiens
GTPase activity
protein binding
GTP binding
...
5
GPX1
ENSG00000233276
H. sapiens
glutathione peroxidase activity
SH3 domain binding
glutathione peroxidase activity
...
13
GRAP2
ENSG00000100351
H. sapiens
SH3/SH2 adaptor activity
protein binding
...
224
GRB2
ENSG00000177885
H. sapiens
phosphotyrosine residue binding
SH3/SH2 adaptor activity
Ras guanyl-nucleotide exchange factor activity
...
2593
GRIP2
ENSG00000144596
H. sapiens
receptor signaling complex scaffold activity
...
1
GRM2
ENSG00000164082
H. sapiens
group II metabotropic glutamate receptor activity
G-protein coupled receptor activity
calcium channel regulator activity
...
5
GSDMC
ENSG00000147697
H. sapiens
molecular_function
...
1
GSK3B
ENSG00000082701
H. sapiens
LITHIUM CARBONATE
LITHIUM CITRATE
RNA polymerase II transcription factor binding
p53 binding
protein kinase activity
...
3867
GSPT1
ENSG00000103342
H. sapiens
translation release factor activity
GTPase activity
protein binding
...
117
GTF2E1
ENSG00000153767
H. sapiens
protein binding
sequence-specific DNA binding
metal ion binding
...
8
GTF2H1
ENSG00000110768
H. sapiens
chromatin binding
protein binding
protein kinase activity
...
3
GTF2H4
ENSG00000226384
H. sapiens
double-stranded DNA binding
double-stranded DNA binding
double-stranded DNA binding
...
26
GTF2I
ENSG00000263001
H. sapiens
RNA polymerase II transcription factor activity, sequence-specific DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
...
1
GTF3C3
ENSG00000119041
H. sapiens
protein binding
transcription factor activity, core RNA polymerase III binding
DNA binding
...
121
GTPBP4
ENSG00000107937
H. sapiens
GTPase activity
protein binding
GTP binding
...
4
HBS1L
ENSG00000112339
H. sapiens
translation elongation factor activity
GTPase activity
GTP binding
...
87
HCAR1
ENSG00000196917
H. sapiens
G-protein coupled receptor activity
...
1
HCCS
ENSG00000004961
H. sapiens
holocytochrome-c synthase activity
metal ion binding
...
2
HCFC1
ENSG00000172534
H. sapiens
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
...
679
HCK
ENSG00000101336
H. sapiens
BOSUTINIB
DASATINIB
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
receptor binding
...
290
HCRT
ENSG00000161610
H. sapiens
neuropeptide hormone activity
type 1 hypocretin receptor binding
type 2 hypocretin receptor binding
...
2
HCRTR1
ENSG00000121764
H. sapiens
SUVOREXANT
G-protein coupled receptor activity
neuropeptide receptor activity
orexin receptor activity
...
3
HDAC1
ENSG00000116478
H. sapiens
BELINOSTAT
PANOBINOSTAT
ROMIDEPSIN
VORINOSTAT
transcription regulatory region sequence-specific DNA binding
core promoter binding
RNA polymerase II transcription factor binding
...
3321
HDAC2
ENSG00000196591
H. sapiens
BELINOSTAT
PANOBINOSTAT
ROMIDEPSIN
VORINOSTAT
core promoter binding
RNA polymerase II repressing transcription factor binding
chromatin binding
...
2603
HDAC6
ENSG00000094631
H. sapiens
BELINOSTAT
PANOBINOSTAT
ROMIDEPSIN
VORINOSTAT
core promoter binding
actin binding
histone deacetylase activity
...
267
HDAC8
ENSG00000147099
H. sapiens
BELINOSTAT
PANOBINOSTAT
ROMIDEPSIN
histone deacetylase activity
protein binding
transcription factor binding
...
12
HEY1
ENSG00000164683
H. sapiens
mesenchymal chondrosarcoma
transcription factor activity, RNA polymerase II core promoter sequence-specific
transcription factor activity, protein binding
transcription factor activity, sequence-specific DNA binding
...
1
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