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Genes
Gene:
Organism:
H. sapiens
S. cerevisiae
S. pombe
D. melanogaster
C. elegans
Type:
SSL
SDL
Quality:
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High Quality Predictions
All
Experimentally Validated
Cancer:
Cancer gene:
Drug search:
Druggable:
Pathway:
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Gene
Ensembl ID
Organism
Diseases
Drugs
Ontology
Interactions
IL12A
ENSG00000168811
H. sapiens
interleukin-12 receptor binding
protein binding
interleukin-12 beta subunit binding
...
2
IL1RAP
ENSG00000196083
H. sapiens
interleukin-33 receptor activity
signal transducer activity
interleukin-1 receptor activity
...
83
IMPDH1
ENSG00000106348
H. sapiens
AZATHIOPRINE
MYCOPHENOLATE MOFETIL
MYCOPHENOLIC ACID
RIBAVIRIN
THIOGUANINE
THIOGUANINE
nucleotide binding
nucleic acid binding
DNA binding
...
84
IMPDH2
ENSG00000178035
H. sapiens
AZATHIOPRINE
MYCOPHENOLATE MOFETIL
MYCOPHENOLIC ACID
THIOGUANINE
THIOGUANINE
nucleotide binding
DNA binding
RNA binding
...
114
ING3
ENSG00000071243
H. sapiens
zinc ion binding
methylated histone binding
histone acetyltransferase activity
...
18
ING4
ENSG00000111653
H. sapiens
transcription coactivator activity
protein binding
zinc ion binding
...
170
ING5
ENSG00000168395
H. sapiens
chromatin binding
protein binding
zinc ion binding
...
179
INO80
ENSG00000128908
H. sapiens
DNA binding
DNA helicase activity
actin binding
...
2363
INO80C
ENSG00000153391
H. sapiens
molecular_function
...
1
INO80D
ENSG00000283510
H. sapiens
...
1
INTS3
ENSG00000143624
H. sapiens
protein binding
protein binding
molecular_function
...
8
INTS5
ENSG00000185085
H. sapiens
protein binding
...
40
INTS9
ENSG00000104299
H. sapiens
protein binding
...
7
IREB2
ENSG00000136381
H. sapiens
RNA binding
protein binding
iron-responsive element binding
...
89
IST1
ENSG00000182149
H. sapiens
protein binding
protein domain specific binding
protein complex binding
...
254
ISY1
ENSG00000240682
H. sapiens
protein binding
first spliceosomal transesterification activity
second spliceosomal transesterification activity
...
100
ITGA6
ENSG00000091409
H. sapiens
integrin binding
protein binding
laminin binding
...
75
ITGB7
ENSG00000139626
H. sapiens
VEDOLIZUMAB
virus receptor activity
protein binding
metal ion binding
...
86
ITM2A
ENSG00000078596
H. sapiens
amyloid-beta binding
protein binding
...
1
JAK1
ENSG00000162434
H. sapiens
ALL
RUXOLITINIB
RUXOLITINIB
TOFACITINIB
TOFACITINIB
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
Ras guanyl-nucleotide exchange factor activity
...
1632
JAK2
ENSG00000096968
H. sapiens
ALL
AML
MPN
CML
RUXOLITINIB
RUXOLITINIB
TOFACITINIB
TOFACITINIB
protein kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
...
2146
JAK3
ENSG00000105639
H. sapiens
acute megakaryocytic leukaemia
ETP ALL
TOFACITINIB
TOFACITINIB
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
Ras guanyl-nucleotide exchange factor activity
...
148
JTB
ENSG00000143543
H. sapiens
protein kinase binding
...
2
KARS
ENSG00000065427
H. sapiens
tRNA binding
lysine-tRNA ligase activity
protein binding
...
379
KAT5
ENSG00000172977
H. sapiens
transcription coactivator activity
histone acetyltransferase activity
protein binding
...
1032
KCMF1
ENSG00000176407
H. sapiens
zinc ion binding
ligase activity
...
29
KCNA3
ENSG00000177272
H. sapiens
DALFAMPRIDINE
GUANIDINE
voltage-gated ion channel activity
delayed rectifier potassium channel activity
outward rectifier potassium channel activity
...
184
KCNH7
ENSG00000184611
H. sapiens
DALFAMPRIDINE
GUANIDINE
voltage-gated potassium channel activity
...
1
KCNQ4
ENSG00000117013
H. sapiens
DALFAMPRIDINE
EZOGABINE
GUANIDINE
delayed rectifier potassium channel activity
potassium channel activity
protein binding
...
4
KCTD10
ENSG00000110906
H. sapiens
protein binding
ubiquitin-protein transferase activity
...
26
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