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Genes
Gene:
Organism:
H. sapiens
S. cerevisiae
S. pombe
D. melanogaster
C. elegans
Type:
SSL
SDL
Quality:
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High Quality Predictions
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Experimentally Validated
Cancer:
Cancer gene:
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Druggable:
Pathway:
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Gene
Ensembl ID
Organism
Diseases
Drugs
Ontology
Interactions
EIF4G2
ENSG00000110321
H. sapiens
translation initiation factor activity
protein binding
translation factor activity, RNA binding
...
215
EIF5B
ENSG00000158417
H. sapiens
translation initiation factor activity
GTPase activity
protein binding
...
3
EIF6
ENSG00000242372
H. sapiens
translation initiation factor activity
protein binding
ribosome binding
...
9
ELP3
ENSG00000134014
H. sapiens
protein binding
phosphorylase kinase regulator activity
H3 histone acetyltransferase activity
...
213
ELP4
ENSG00000109911
H. sapiens
protein binding
phosphorylase kinase regulator activity
RNA polymerase II core binding
...
154
EMC1
ENSG00000127463
H. sapiens
molecular_function
molecular_function
...
95
EMC2
ENSG00000104412
H. sapiens
protein binding
molecular_function
...
13
EMC4
ENSG00000128463
H. sapiens
molecular_function
molecular_function
...
66
EMC6
ENSG00000127774
H. sapiens
protein binding
molecular_function
...
4
EMC7
ENSG00000134153
H. sapiens
carbohydrate binding
...
10
EMG1
ENSG00000268439
H. sapiens
RNA binding
RNA binding
protein binding
...
3
EMID1
ENSG00000186998
H. sapiens
...
1
ENPP4
ENSG00000001561
H. sapiens
metal ion binding
bis(5'-adenosyl)-triphosphatase activity
...
1
ENPP5
ENSG00000112796
H. sapiens
hydrolase activity
metal ion binding
...
1
EP300
ENSG00000100393
H. sapiens
colorectal
breast
pancreatic
AML
ALL
DLBCL
RNA polymerase II core promoter sequence-specific DNA binding
core promoter binding
RNA polymerase II activating transcription factor binding
...
2308
EP400
ENSG00000183495
H. sapiens
DNA binding
chromatin binding
helicase activity
...
369
EPC1
ENSG00000120616
H. sapiens
protein binding
histone acetyltransferase activity
...
190
EPHA2
ENSG00000142627
H. sapiens
DASATINIB
VANDETANIB
transmembrane receptor protein tyrosine kinase activity
ephrin receptor activity
protein binding
...
2
EPHB2
ENSG00000133216
H. sapiens
VANDETANIB
protein tyrosine kinase activity
transmembrane-ephrin receptor activity
receptor binding
...
155
EPHB4
ENSG00000196411
H. sapiens
VANDETANIB
transmembrane receptor protein tyrosine kinase activity
ephrin receptor activity
protein binding
...
42
EPOR
ENSG00000187266
H. sapiens
DARBEPOETIN ALFA
EPOETIN ALFA
PEGINESATIDE ACETATE
erythropoietin receptor activity
protein binding
identical protein binding
...
325
EPRS
ENSG00000136628
H. sapiens
glutamate-tRNA ligase activity
proline-tRNA ligase activity
protein binding
...
1127
ERBB2
ENSG00000141736
H. sapiens
breast
ovarian
other tumour types
NSCLC
gastric
AFATINIB
LAPATINIB
PERTUZUMAB
TRASTUZUMAB
TRASTUZUMAB EMTANSINE
VANDETANIB
RNA polymerase I core binding
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
...
1969
ERBB3
ENSG00000065361
H. sapiens
colon
gastric
head and neck
bladder
skin
VANDETANIB
protein tyrosine kinase activity
transmembrane signaling receptor activity
Ras guanyl-nucleotide exchange factor activity
...
58
ERH
ENSG00000100632
H. sapiens
protein binding
methyl-CpG binding
...
59
ERN1
ENSG00000178607
H. sapiens
magnesium ion binding
endoribonuclease activity
protein serine/threonine kinase activity
...
282
EXOC2
ENSG00000112685
H. sapiens
protein binding
Ral GTPase binding
protein kinase binding
...
197
EXOC4
ENSG00000131558
H. sapiens
protein binding
Ral GTPase binding
PDZ domain binding
...
233
EXOSC10
ENSG00000171824
H. sapiens
nucleotide binding
3'-5'-exoribonuclease activity
exoribonuclease activity
...
568
EXOSC2
ENSG00000130713
H. sapiens
3'-5'-exoribonuclease activity
protein binding
7S RNA binding
...
278
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