POLA1

ENSG00000101868 - H. sapiens

Pathways

Go term Description
GO:0000166 nucleotide binding
GO:0001882 nucleoside binding
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0005515 protein binding
GO:0008408 3'-5' exonuclease activity
GO:0019901 protein kinase binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0003896 DNA primase activity

Drugs

Drug name Description
CLOFARABINE DNA inhibitor
CYTARABINE DNA polymerase (alpha/delta/epsilon) inhibitor
FLUDARABINE PHOSPHATE DNA polymerase (alpha/delta/epsilon) inhibitor
GEMCITABINE
NELARABINE

Diseases

No diseases in record

Orthologs

Gene Organism
POL1 S. cerevisiae
DNApol-alpha180 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000101868 POLA1 ENSG00000126457 PRMT1 H. sapiens SSL Slorth 0.968288 View
ENSG00000101868 POLA1 ENSG00000163930 BAP1 H. sapiens SSL Slorth 0.968149 View
ENSG00000101868 POLA1 ENSG00000103197 TSC2 H. sapiens SSL Slorth 0.968086 View
ENSG00000101868 POLA1 ENSG00000117133 RPF1 H. sapiens SSL Slorth 0.968061 View
ENSG00000101868 POLA1 ENSG00000112578 BYSL H. sapiens SSL Slorth 0.96806 View
ENSG00000101868 POLA1 ENSG00000171791 BCL2 H. sapiens SSL Slorth 0.968045 View
ENSG00000101868 POLA1 ENSG00000118503 TNFAIP3 H. sapiens SSL Slorth 0.968031 View
ENSG00000101868 POLA1 ENSG00000165280 VCP H. sapiens SSL Slorth 0.967946 View
ENSG00000101868 POLA1 ENSG00000105325 FZR1 H. sapiens SSL Slorth 0.967794 View
ENSG00000101868 POLA1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.967758 View
ENSG00000101868 POLA1 ENSG00000103126 AXIN1 H. sapiens SSL Slorth 0.967601 View
ENSG00000101868 POLA1 ENSG00000156970 BUB1B H. sapiens SSL Slorth 0.96758 View
ENSG00000101361 NOP56 ENSG00000101868 POLA1 H. sapiens SDL Slorth 0.967573 View
ENSG00000101868 POLA1 ENSG00000127445 PIN1 H. sapiens SSL Slorth 0.967422 View
ENSG00000101868 POLA1 ENSG00000137076 TLN1 H. sapiens SSL Slorth 0.967404 View
ENSG00000101868 POLA1 ENSG00000134057 CCNB1 H. sapiens SSL Slorth 0.967298 View
ENSG00000101868 POLA1 ENSG00000113575 PPP2CA H. sapiens SSL Slorth 0.967242 View
ENSG00000101868 POLA1 ENSG00000105810 CDK6 H. sapiens SSL Slorth 0.967186 View
ENSG00000097046 CDC7 ENSG00000101868 POLA1 H. sapiens SDL Slorth 0.96717 View
ENSG00000101868 POLA1 ENSG00000184634 MED12 H. sapiens SSL Slorth 0.967125 View
ENSG00000101868 POLA1 ENSG00000124181 PLCG1 H. sapiens SSL Slorth 0.967064 View
ENSG00000101868 POLA1 ENSG00000131508 UBE2D2 H. sapiens SSL Slorth 0.966808 View
ENSG00000101868 POLA1 ENSG00000107581 EIF3A H. sapiens SSL Slorth 0.966797 View
ENSG00000101868 POLA1 ENSG00000167986 DDB1 H. sapiens SSL Slorth 0.966661 View
ENSG00000101868 POLA1 ENSG00000168036 CTNNB1 H. sapiens SDL Slorth 0.966593 View
ENSG00000096717 SIRT1 ENSG00000101868 POLA1 H. sapiens SSL Slorth 0.966468 View
ENSG00000101868 POLA1 ENSG00000170312 CDK1 H. sapiens SSL Slorth 0.966355 View
ENSG00000101868 POLA1 ENSG00000188486 H2AFX H. sapiens SSL Slorth 0.966253 View
ENSG00000100030 MAPK1 ENSG00000101868 POLA1 H. sapiens SSL Slorth 0.966239 View
ENSG00000004897 CDC27 ENSG00000101868 POLA1 H. sapiens SDL Slorth 0.966172 View
ENSG00000101412 E2F1 ENSG00000101868 POLA1 H. sapiens SSL Slorth 0.966116 View
ENSG00000101868 POLA1 ENSG00000173473 SMARCC1 H. sapiens SSL Slorth 0.966038 View
ENSG00000101868 POLA1 ENSG00000124813 RUNX2 H. sapiens SSL Slorth 0.966016 View
ENSG00000101868 POLA1 ENSG00000134308 YWHAQ H. sapiens SSL Slorth 0.965985 View
ENSG00000101868 POLA1 ENSG00000108443 RPS6KB1 H. sapiens SSL Slorth 0.965898 View
ENSG00000101868 POLA1 ENSG00000140464 PML H. sapiens SSL Slorth 0.965722 View
ENSG00000012048 BRCA1 ENSG00000101868 POLA1 H. sapiens SSL Slorth 0.965713 View
ENSG00000101868 POLA1 ENSG00000134982 APC H. sapiens SSL Slorth 0.965615 View
ENSG00000101868 POLA1 ENSG00000143033 MTF2 H. sapiens SDL Slorth 0.965606 View
ENSG00000101868 POLA1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.965543 View