POLA1

ENSG00000101868 - H. sapiens

Pathways

Go term Description
GO:0000166 nucleotide binding
GO:0001882 nucleoside binding
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0005515 protein binding
GO:0008408 3'-5' exonuclease activity
GO:0019901 protein kinase binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0003896 DNA primase activity

Drugs

Drug name Description
CLOFARABINE DNA inhibitor
CYTARABINE DNA polymerase (alpha/delta/epsilon) inhibitor
FLUDARABINE PHOSPHATE DNA polymerase (alpha/delta/epsilon) inhibitor
GEMCITABINE
NELARABINE

Diseases

No diseases in record

Orthologs

Gene Organism
POL1 S. cerevisiae
DNApol-alpha180 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000101868 POLA1 ENSG00000158125 XDH H. sapiens SSL Slorth 0.796007 View
ENSG00000101868 POLA1 ENSG00000164588 HCN1 H. sapiens SSL Slorth 0.796007 View
ENSG00000101868 POLA1 ENSG00000134278 SPIRE1 H. sapiens SSL Slorth 0.796007 View
ENSG00000101868 POLA1 ENSG00000139287 TPH2 H. sapiens SSL Slorth 0.796007 View
ENSG00000101868 POLA1 ENSG00000197646 PDCD1LG2 H. sapiens SSL Slorth 0.796007 View
ENSG00000101868 POLA1 ENSG00000122728 TAF1L H. sapiens SSL Slorth 0.79592 View
ENSG00000101868 POLA1 ENSG00000128578 STRIP2 H. sapiens SSL Slorth 0.795729 View
ENSG00000101868 POLA1 ENSG00000169760 NLGN1 H. sapiens SSL Slorth 0.793938 View
ENSG00000101868 POLA1 ENSG00000160214 RRP1 H. sapiens SSL Slorth 0.793848 View
ENSG00000090020 SLC9A1 ENSG00000101868 POLA1 H. sapiens SSL Slorth 0.793228 View
ENSG00000101868 POLA1 ENSG00000112406 HECA H. sapiens SSL Slorth 0.793039 View
ENSG00000101868 POLA1 ENSG00000108510 MED13 H. sapiens SSL Slorth 0.792673 View
ENSG00000101868 POLA1 ENSG00000168036 CTNNB1 H. sapiens SSL Slorth 0.792648 View
ENSG00000101868 POLA1 ENSG00000155111 CDK19 H. sapiens SSL Slorth 0.792188 View
ENSG00000101868 POLA1 ENSG00000183580 FBXL7 H. sapiens SSL Slorth 0.791752 View
ENSG00000101868 POLA1 ENSG00000113460 BRIX1 H. sapiens SSL Slorth 0.788834 View
ENSG00000009413 REV3L ENSG00000101868 POLA1 H. sapiens SSL Slorth 0.788725 View
ENSG00000101442 ACTR5 ENSG00000101868 POLA1 H. sapiens SSL Slorth 0.787277 View
ENSG00000101868 POLA1 ENSG00000155816 FMN2 H. sapiens SSL Slorth 0.785533 View
ENSG00000101868 POLA1 ENSG00000139410 SDSL H. sapiens SSL Slorth 0.785533 View
ENSG00000049246 PER3 ENSG00000101868 POLA1 H. sapiens SSL Slorth 0.783562 View
ENSG00000011304 PTBP1 ENSG00000101868 POLA1 H. sapiens SSL Slorth 0.782034 View
ENSG00000101868 POLA1 ENSG00000160199 PKNOX1 H. sapiens SSL Slorth 0.781298 View
ENSG00000101868 POLA1 ENSG00000198301 SDAD1 H. sapiens SSL Slorth 0.779992 View
ENSG00000057657 PRDM1 ENSG00000101868 POLA1 H. sapiens SSL Slorth 0.778331 View
ENSG00000078304 PPP2R5C ENSG00000101868 POLA1 H. sapiens SSL Slorth 0.778227 View
ENSG00000099995 SF3A1 ENSG00000101868 POLA1 H. sapiens SSL Slorth 0.776331 View
ENSG00000028839 TBPL1 ENSG00000101868 POLA1 H. sapiens SSL Slorth 0.776111 View
ENSG00000101868 POLA1 ENSG00000102781 KATNAL1 H. sapiens SSL Slorth 0.774305 View
ENSG00000101849 TBL1X ENSG00000101868 POLA1 H. sapiens SSL Slorth 0.773534 View
ENSG00000072310 SREBF1 ENSG00000101868 POLA1 H. sapiens SSL Slorth 0.772772 View
ENSG00000101868 POLA1 ENSG00000165819 METTL3 H. sapiens SSL Slorth 0.769648 View
ENSG00000080608 PUM3 ENSG00000101868 POLA1 H. sapiens SSL Slorth 0.76962 View
ENSG00000099381 SETD1A ENSG00000101868 POLA1 H. sapiens SSL Slorth 0.769014 View
ENSG00000085733 CTTN ENSG00000101868 POLA1 H. sapiens SSL Slorth 0.768193 View
ENSG00000020922 MRE11 ENSG00000101868 POLA1 H. sapiens SSL Slorth 0.767177 View
ENSG00000065054 SLC9A3R2 ENSG00000101868 POLA1 H. sapiens SSL Slorth 0.765341 View
ENSG00000101868 POLA1 ENSG00000116478 HDAC1 H. sapiens SSL Slorth 0.763362 View
ENSG00000101868 POLA1 ENSG00000171126 KCNG3 H. sapiens SSL Slorth 0.76326 View
ENSG00000035403 VCL ENSG00000101868 POLA1 H. sapiens SSL Slorth 0.762973 View