FGFR2

ENSG00000066468 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0005007 fibroblast growth factor-activated receptor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008201 heparin binding
GO:0016303 1-phosphatidylinositol-3-kinase activity
GO:0017134 fibroblast growth factor binding
GO:0042803 protein homodimerization activity
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity

Drugs

Drug name Description
NINTEDANIB Platelet-derived growth factor receptor inhibitor
PALIFERMIN Fibroblast growth factor receptor 2 agonist
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
gastric
NSCLC
endometrial

Orthologs

Gene Organism
egl-15 C. elegans
htl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000066468 FGFR2 ENSG00000164885 CDK5 H. sapiens SSL Slorth 0.930767 View
ENSG00000066468 FGFR2 ENSG00000106462 EZH2 H. sapiens SSL Slorth 0.930767 View
ENSG00000066468 FGFR2 ENSG00000157404 KIT H. sapiens SSL Slorth 0.930642 View
ENSG00000066468 FGFR2 ENSG00000108094 CUL2 H. sapiens SSL Slorth 0.930456 View
ENSG00000066468 FGFR2 ENSG00000181163 NPM1 H. sapiens SSL Slorth 0.930194 View
ENSG00000066468 FGFR2 ENSG00000100297 MCM5 H. sapiens SSL Slorth 0.92995 View
ENSG00000066468 FGFR2 ENSG00000103479 RBL2 H. sapiens SSL Slorth 0.929775 View
ENSG00000066468 FGFR2 ENSG00000196470 SIAH1 H. sapiens SSL Slorth 0.929701 View
ENSG00000066468 FGFR2 ENSG00000132466 ANKRD17 H. sapiens SDL Slorth 0.929559 View
ENSG00000066468 FGFR2 ENSG00000175054 ATR H. sapiens SSL Slorth 0.929479 View
ENSG00000066468 FGFR2 ENSG00000112144 ICK H. sapiens SDL Slorth 0.92937 View
ENSG00000066468 FGFR2 ENSG00000105810 CDK6 H. sapiens SSL Slorth 0.92922 View
ENSG00000066468 FGFR2 ENSG00000104738 MCM4 H. sapiens SSL Slorth 0.929055 View
ENSG00000066468 FGFR2 ENSG00000078747 ITCH H. sapiens SSL Slorth 0.928947 View
ENSG00000066468 FGFR2 ENSG00000099956 SMARCB1 H. sapiens SSL Slorth 0.928806 View
ENSG00000066468 FGFR2 ENSG00000070159 PTPN3 H. sapiens SDL Slorth 0.928725 View
ENSG00000066468 FGFR2 ENSG00000138795 LEF1 H. sapiens SDL Slorth 0.928644 View
ENSG00000066468 FGFR2 ENSG00000185359 HGS H. sapiens SSL Slorth 0.928584 View
ENSG00000066468 FGFR2 ENSG00000133703 KRAS H. sapiens SSL Slorth 0.928408 View
ENSG00000066468 FGFR2 ENSG00000154229 PRKCA H. sapiens SSL Slorth 0.92837 View
ENSG00000066468 FGFR2 ENSG00000134086 VHL H. sapiens SSL Slorth 0.928154 View
ENSG00000066468 FGFR2 ENSG00000131747 TOP2A H. sapiens SSL Slorth 0.928015 View
ENSG00000066468 FGFR2 ENSG00000197299 BLM H. sapiens SSL Slorth 0.927865 View
ENSG00000066468 FGFR2 ENSG00000196419 XRCC6 H. sapiens SSL Slorth 0.927836 View
ENSG00000066468 FGFR2 ENSG00000254087 LYN H. sapiens SSL Slorth 0.927713 View
ENSG00000066468 FGFR2 ENSG00000114166 KAT2B H. sapiens SSL Slorth 0.927473 View
ENSG00000066468 FGFR2 ENSG00000132170 PPARG H. sapiens SSL Slorth 0.92728 View
ENSG00000066468 FGFR2 ENSG00000115904 SOS1 H. sapiens SSL Slorth 0.927087 View
ENSG00000066468 FGFR2 ENSG00000089159 PXN H. sapiens SSL Slorth 0.926978 View
ENSG00000066468 FGFR2 ENSG00000169375 SIN3A H. sapiens SDL Slorth 0.926828 View
ENSG00000066468 FGFR2 ENSG00000147065 MSN H. sapiens SDL Slorth 0.926773 View
ENSG00000066468 FGFR2 ENSG00000101412 E2F1 H. sapiens SSL Slorth 0.926748 View
ENSG00000066468 FGFR2 ENSG00000145604 SKP2 H. sapiens SSL Slorth 0.926278 View
ENSG00000066468 FGFR2 ENSG00000117676 RPS6KA1 H. sapiens SSL Slorth 0.926211 View
ENSG00000066468 FGFR2 ENSG00000080503 SMARCA2 H. sapiens SSL Slorth 0.926198 View
ENSG00000066468 FGFR2 ENSG00000172977 KAT5 H. sapiens SSL Slorth 0.926048 View
ENSG00000066468 FGFR2 ENSG00000166200 COPS2 H. sapiens SSL Slorth 0.925971 View
ENSG00000066468 FGFR2 ENSG00000100030 MAPK1 H. sapiens SDL Slorth 0.925954 View
ENSG00000066468 FGFR2 ENSG00000143190 POU2F1 H. sapiens SSL Slorth 0.925661 View
ENSG00000066468 FGFR2 ENSG00000128052 KDR H. sapiens SSL Slorth 0.925628 View