SMAD2

ENSG00000175387 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003690 double-stranded DNA binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0005160 transforming growth factor beta receptor binding
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0019902 phosphatase binding
GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
GO:0031625 ubiquitin protein ligase binding
GO:0033613 activating transcription factor binding
GO:0034713 type I transforming growth factor beta receptor binding
GO:0035326 enhancer binding
GO:0042803 protein homodimerization activity
GO:0046332 SMAD binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0070410 co-SMAD binding
GO:0070411 I-SMAD binding
GO:0070412 R-SMAD binding
GO:0003677 DNA binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal carcinoma
hepatocellular carcinoma

Orthologs

Gene Organism
sma-3 C. elegans
sma-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000070831 CDC42 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.934605 View
ENSG00000026103 FAS ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.934493 View
ENSG00000175387 SMAD2 ENSG00000183765 CHEK2 H. sapiens SSL Slorth 0.934484 View
ENSG00000063245 EPN1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.934477 View
ENSG00000138814 PPP3CA ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.934394 View
ENSG00000078747 ITCH ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.934075 View
ENSG00000150768 DLAT ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.933966 View
ENSG00000067992 PDK3 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.933966 View
ENSG00000096384 HSP90AB1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.9339 View
ENSG00000101361 NOP56 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.9339 View
ENSG00000164104 HMGB2 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.933896 View
ENSG00000142534 RPS11 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.933783 View
ENSG00000136504 KAT7 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.933749 View
ENSG00000162409 PRKAA2 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.933737 View
ENSG00000156482 RPL30 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.933655 View
ENSG00000169032 MAP2K1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.933574 View
ENSG00000100906 NFKBIA ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.933519 View
ENSG00000175387 SMAD2 ENSG00000184009 ACTG1 H. sapiens SDL Slorth 0.933481 View
ENSG00000028277 POU2F2 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.933439 View
ENSG00000167658 EEF2 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.933243 View
ENSG00000175387 SMAD2 ENSG00000184428 TOP1MT H. sapiens SDL Slorth 0.933194 View
ENSG00000175387 SMAD2 ENSG00000204842 ATXN2 H. sapiens SSL Slorth 0.933165 View
ENSG00000138795 LEF1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.933163 View
ENSG00000139746 RBM26 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.933029 View
ENSG00000084676 NCOA1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.932903 View
ENSG00000051180 RAD51 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.932804 View
ENSG00000122692 SMU1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.932799 View
ENSG00000113558 SKP1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.932777 View
ENSG00000089157 RPLP0 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.932552 View
ENSG00000125977 EIF2S2 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.932525 View
ENSG00000126457 PRMT1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.932422 View
ENSG00000118689 FOXO3 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.932389 View
ENSG00000163017 ACTG2 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.932385 View
ENSG00000071626 DAZAP1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.932385 View
ENSG00000103657 HERC1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.932385 View
ENSG00000116791 CRYZ ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.932385 View
ENSG00000138641 HERC3 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.932385 View
ENSG00000151292 CSNK1G3 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.932385 View
ENSG00000066279 ASPM ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.932385 View
ENSG00000112245 PTP4A1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.932385 View