SMAD2

ENSG00000175387 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003690 double-stranded DNA binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0005160 transforming growth factor beta receptor binding
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0019902 phosphatase binding
GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
GO:0031625 ubiquitin protein ligase binding
GO:0033613 activating transcription factor binding
GO:0034713 type I transforming growth factor beta receptor binding
GO:0035326 enhancer binding
GO:0042803 protein homodimerization activity
GO:0046332 SMAD binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0070410 co-SMAD binding
GO:0070411 I-SMAD binding
GO:0070412 R-SMAD binding
GO:0003677 DNA binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal carcinoma
hepatocellular carcinoma

Orthologs

Gene Organism
sma-3 C. elegans
sma-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000127152 BCL11B ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.942186 View
ENSG00000025796 SEC63 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.942038 View
ENSG00000110395 CBL ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.942033 View
ENSG00000134333 LDHA ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.942 View
ENSG00000118503 TNFAIP3 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.941956 View
ENSG00000086065 CHMP5 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.941944 View
ENSG00000149782 PLCB3 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.941916 View
ENSG00000148634 HERC4 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.941868 View
ENSG00000127663 KDM4B ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.941868 View
ENSG00000117143 UAP1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.941868 View
ENSG00000109814 UGDH ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.941868 View
ENSG00000011405 PIK3C2A ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.941868 View
ENSG00000164070 HSPA4L ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.941868 View
ENSG00000114491 UMPS ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.941868 View
ENSG00000070010 UFD1L ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.94184 View
ENSG00000135476 ESPL1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.941833 View
ENSG00000141646 SMAD4 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.94181 View
ENSG00000066136 NFYC ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.941686 View
ENSG00000175387 SMAD2 ENSG00000189403 HMGB1 H. sapiens SDL Slorth 0.941647 View
ENSG00000062650 WAPL ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.941579 View
ENSG00000109332 UBE2D3 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.941541 View
ENSG00000119866 BCL11A ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.94154 View
ENSG00000100387 RBX1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.941477 View
ENSG00000175387 SMAD2 ENSG00000204390 HSPA1L H. sapiens SDL Slorth 0.941402 View
ENSG00000144554 FANCD2 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.941341 View
ENSG00000159461 AMFR ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.941311 View
ENSG00000175387 SMAD2 ENSG00000176749 CDK5R1 H. sapiens SDL Slorth 0.941282 View
ENSG00000118007 STAG1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.941254 View
ENSG00000162613 FUBP1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.941239 View
ENSG00000159210 SNF8 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.941215 View
ENSG00000099956 SMARCB1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.94121 View
ENSG00000175387 SMAD2 ENSG00000198793 MTOR H. sapiens SDL Slorth 0.941206 View
ENSG00000073921 PICALM ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.9412 View
ENSG00000115464 USP34 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.941117 View
ENSG00000096968 JAK2 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.941026 View
ENSG00000145715 RASA1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.941002 View
ENSG00000166477 LEO1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.940976 View
ENSG00000106588 PSMA2 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.940874 View
ENSG00000108946 PRKAR1A ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.940826 View
ENSG00000101811 CSTF2 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.940755 View