SMAD2

ENSG00000175387 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003690 double-stranded DNA binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0005160 transforming growth factor beta receptor binding
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0019902 phosphatase binding
GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
GO:0031625 ubiquitin protein ligase binding
GO:0033613 activating transcription factor binding
GO:0034713 type I transforming growth factor beta receptor binding
GO:0035326 enhancer binding
GO:0042803 protein homodimerization activity
GO:0046332 SMAD binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0070410 co-SMAD binding
GO:0070411 I-SMAD binding
GO:0070412 R-SMAD binding
GO:0003677 DNA binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal carcinoma
hepatocellular carcinoma

Orthologs

Gene Organism
sma-3 C. elegans
sma-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000103479 RBL2 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.947397 View
ENSG00000143398 PIP5K1A ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.947322 View
ENSG00000159263 SIM2 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.947284 View
ENSG00000082014 SMARCD3 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.947255 View
ENSG00000141968 VAV1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.947252 View
ENSG00000171791 BCL2 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.947151 View
ENSG00000085840 ORC1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.947147 View
ENSG00000154229 PRKCA ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.947109 View
ENSG00000103126 AXIN1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.947079 View
ENSG00000175387 SMAD2 ENSG00000183207 RUVBL2 H. sapiens SDL Slorth 0.947042 View
ENSG00000175387 SMAD2 ENSG00000198625 MDM4 H. sapiens SSL Slorth 0.946952 View
ENSG00000168092 PAFAH1B2 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.946917 View
ENSG00000071794 HLTF ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.946905 View
ENSG00000123836 PFKFB2 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.946844 View
ENSG00000168374 ARF4 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.946844 View
ENSG00000170385 SLC30A1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.946844 View
ENSG00000114374 USP9Y ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.946844 View
ENSG00000165304 MELK ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.946844 View
ENSG00000155974 GRIP1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.946828 View
ENSG00000145386 CCNA2 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.946819 View
ENSG00000168883 USP39 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.946775 View
ENSG00000175387 SMAD2 ENSG00000188021 UBQLN2 H. sapiens SDL Slorth 0.946629 View
ENSG00000097007 ABL1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.946484 View
ENSG00000100968 NFATC4 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.94634 View
ENSG00000124232 RBPJL ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.946261 View
ENSG00000101752 MIB1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.94622 View
ENSG00000175387 SMAD2 ENSG00000180098 TRNAU1AP H. sapiens SDL Slorth 0.946178 View
ENSG00000175387 SMAD2 ENSG00000205531 NAP1L4 H. sapiens SSL Slorth 0.946168 View
ENSG00000078043 PIAS2 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.946116 View
ENSG00000130479 MAP1S ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.946016 View
ENSG00000132356 PRKAA1 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.94591 View
ENSG00000119729 RHOQ ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.94582 View
ENSG00000119699 TGFB3 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.94575 View
ENSG00000175387 SMAD2 ENSG00000197102 DYNC1H1 H. sapiens SDL Slorth 0.945703 View
ENSG00000173473 SMARCC1 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.945666 View
ENSG00000109971 HSPA8 ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.945531 View
ENSG00000074319 TSG101 ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.945523 View
ENSG00000175387 SMAD2 ENSG00000253729 PRKDC H. sapiens SDL Slorth 0.945503 View
ENSG00000175387 SMAD2 ENSG00000187741 FANCA H. sapiens SDL Slorth 0.945502 View
ENSG00000114166 KAT2B ENSG00000175387 SMAD2 H. sapiens SDL Slorth 0.945468 View