CDK7

ENSG00000134058 - H. sapiens

Pathways

Go term Description
GO:0003713 transcription coactivator activity
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004693 cyclin-dependent protein serine/threonine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0008094 DNA-dependent ATPase activity
GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity
GO:0016301 kinase activity
GO:0050681 androgen receptor binding
GO:0000990 transcription factor activity, core RNA polymerase binding

Drugs

No drugs in record

Diseases

No diseases in record

Orthologs

Gene Organism
KIN28 S. cerevisiae
cdk-7 C. elegans
Cdk7 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000134058 CDK7 H. sapiens SDL Slorth 0.98889 View
ENSG00000132646 PCNA ENSG00000134058 CDK7 H. sapiens SDL Slorth 0.988179 View
ENSG00000116478 HDAC1 ENSG00000134058 CDK7 H. sapiens SDL Slorth 0.987061 View
ENSG00000113558 SKP1 ENSG00000134058 CDK7 H. sapiens SDL Slorth 0.986094 View
ENSG00000012048 BRCA1 ENSG00000134058 CDK7 H. sapiens SDL Slorth 0.983341 View
ENSG00000101266 CSNK2A1 ENSG00000134058 CDK7 H. sapiens SDL Slorth 0.982191 View
ENSG00000100393 EP300 ENSG00000134058 CDK7 H. sapiens SDL Slorth 0.981253 View
ENSG00000123374 CDK2 ENSG00000134058 CDK7 H. sapiens SDL Slorth 0.980848 View
ENSG00000134058 CDK7 ENSG00000169083 AR H. sapiens SDL Slorth 0.979006 View
ENSG00000005339 CREBBP ENSG00000134058 CDK7 H. sapiens SDL Slorth 0.97889 View
ENSG00000132383 RPA1 ENSG00000134058 CDK7 H. sapiens SDL Slorth 0.977226 View
ENSG00000134058 CDK7 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.977214 View
ENSG00000110395 CBL ENSG00000134058 CDK7 H. sapiens SDL Slorth 0.976158 View
ENSG00000109670 FBXW7 ENSG00000134058 CDK7 H. sapiens SSL Slorth 0.975747 View
ENSG00000134058 CDK7 ENSG00000146648 EGFR H. sapiens SDL Slorth 0.974604 View
ENSG00000134058 CDK7 ENSG00000150991 UBC H. sapiens SDL Slorth 0.97427 View
ENSG00000080824 HSP90AA1 ENSG00000134058 CDK7 H. sapiens SDL Slorth 0.973643 View
ENSG00000112592 TBP ENSG00000134058 CDK7 H. sapiens SDL Slorth 0.973316 View
ENSG00000124762 CDKN1A ENSG00000134058 CDK7 H. sapiens SDL Slorth 0.972208 View
ENSG00000134058 CDK7 ENSG00000141510 TP53 H. sapiens SDL Slorth 0.971604 View
ENSG00000133703 KRAS ENSG00000134058 CDK7 H. sapiens SSL Slorth 0.971275 View
ENSG00000116030 SUMO1 ENSG00000134058 CDK7 H. sapiens SSL Slorth 0.968298 View
ENSG00000113575 PPP2CA ENSG00000134058 CDK7 H. sapiens SDL Slorth 0.967389 View
ENSG00000134058 CDK7 ENSG00000145604 SKP2 H. sapiens SDL Slorth 0.965747 View
ENSG00000111276 CDKN1B ENSG00000134058 CDK7 H. sapiens SDL Slorth 0.964191 View
ENSG00000005339 CREBBP ENSG00000134058 CDK7 H. sapiens SSL Slorth 0.963014 View
ENSG00000101412 E2F1 ENSG00000134058 CDK7 H. sapiens SDL Slorth 0.96264 View
ENSG00000134058 CDK7 ENSG00000139687 RB1 H. sapiens SDL Slorth 0.961243 View
ENSG00000110107 PRPF19 ENSG00000134058 CDK7 H. sapiens SDL Slorth 0.961107 View
ENSG00000134058 CDK7 ENSG00000168036 CTNNB1 H. sapiens SDL Slorth 0.960623 View
ENSG00000134058 CDK7 ENSG00000170312 CDK1 H. sapiens SDL Slorth 0.960335 View
ENSG00000101266 CSNK2A1 ENSG00000134058 CDK7 H. sapiens SSL Slorth 0.959989 View
ENSG00000012048 BRCA1 ENSG00000134058 CDK7 H. sapiens SSL Slorth 0.959885 View
ENSG00000002016 RAD52 ENSG00000134058 CDK7 H. sapiens SDL Slorth 0.95419 View
ENSG00000134058 CDK7 ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.953591 View
ENSG00000134058 CDK7 ENSG00000145386 CCNA2 H. sapiens SDL Slorth 0.952998 View
ENSG00000103275 UBE2I ENSG00000134058 CDK7 H. sapiens SSL Slorth 0.952517 View
ENSG00000123374 CDK2 ENSG00000134058 CDK7 H. sapiens SSL Slorth 0.951963 View
ENSG00000091831 ESR1 ENSG00000134058 CDK7 H. sapiens SSL Slorth 0.951406 View
ENSG00000110395 CBL ENSG00000134058 CDK7 H. sapiens SSL Slorth 0.950973 View