CDK4

ENSG00000135446 - H. sapiens

Pathways

Go term Description
GO:0004693 cyclin-dependent protein serine/threonine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
GO:0030332 cyclin binding
GO:0032403 protein complex binding
GO:0004674 protein serine/threonine kinase activity

Drugs

Drug name Description
PALBOCICLIB CDK4/cyclin D1 inhibitor

Diseases

Disease Name
melanoma

Orthologs

Gene Organism
CDC28 S. cerevisiae
cdk-4 C. elegans
Cdk4 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000102882 MAPK3 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.959483 View
ENSG00000135446 CDK4 ENSG00000178999 AURKB H. sapiens SDL Slorth 0.959425 View
ENSG00000135446 CDK4 ENSG00000157933 SKI H. sapiens SSL Slorth 0.959313 View
ENSG00000110092 CCND1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.959258 View
ENSG00000135446 CDK4 ENSG00000185022 MAFF H. sapiens SDL Slorth 0.959211 View
ENSG00000135446 CDK4 ENSG00000136021 SCYL2 H. sapiens SDL Slorth 0.959068 View
ENSG00000108094 CUL2 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.959064 View
ENSG00000135446 CDK4 ENSG00000164924 YWHAZ H. sapiens SSL Slorth 0.958932 View
ENSG00000113721 PDGFRB ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.958927 View
ENSG00000110031 LPXN ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.958908 View
ENSG00000121481 RNF2 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.958886 View
ENSG00000135446 CDK4 ENSG00000184937 WT1 H. sapiens SDL Slorth 0.958846 View
ENSG00000135446 CDK4 ENSG00000138668 HNRNPD H. sapiens SDL Slorth 0.958825 View
ENSG00000123124 WWP1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.958673 View
ENSG00000094916 CBX5 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.958489 View
ENSG00000112062 MAPK14 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.958441 View
ENSG00000094804 CDC6 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.958315 View
ENSG00000078140 UBE2K ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.958313 View
ENSG00000135446 CDK4 ENSG00000150753 CCT5 H. sapiens SSL Slorth 0.95824 View
ENSG00000135446 CDK4 ENSG00000163930 BAP1 H. sapiens SSL Slorth 0.958132 View
ENSG00000135446 CDK4 ENSG00000198176 TFDP1 H. sapiens SDL Slorth 0.95806 View
ENSG00000132646 PCNA ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.958026 View
ENSG00000130939 UBE4B ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.958018 View
ENSG00000129245 FXR2 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.95795 View
ENSG00000132386 SERPINF1 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.95795 View
ENSG00000135446 CDK4 ENSG00000139842 CUL4A H. sapiens SSL Slorth 0.957884 View
ENSG00000079134 THOC1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.957746 View
ENSG00000135446 CDK4 ENSG00000175054 ATR H. sapiens SSL Slorth 0.957644 View
ENSG00000123200 ZC3H13 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.957454 View
ENSG00000100320 RBFOX2 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.957378 View
ENSG00000135446 CDK4 ENSG00000169750 RAC3 H. sapiens SSL Slorth 0.95732 View
ENSG00000135446 CDK4 ENSG00000147162 OGT H. sapiens SDL Slorth 0.957172 View
ENSG00000135446 CDK4 ENSG00000166483 WEE1 H. sapiens SDL Slorth 0.957136 View
ENSG00000135446 CDK4 ENSG00000142208 AKT1 H. sapiens SDL Slorth 0.957117 View
ENSG00000099817 POLR2E ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.957102 View
ENSG00000085999 RAD54L ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.957093 View
ENSG00000135446 CDK4 ENSG00000173039 RELA H. sapiens SSL Slorth 0.957074 View
ENSG00000105974 CAV1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.95706 View
ENSG00000135446 CDK4 ENSG00000187098 MITF H. sapiens SDL Slorth 0.957048 View
ENSG00000132341 RAN ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.956991 View