POLR2E - CDK4

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
POLR2E	ENSG00000099817	No diseases in record	No drugs in record	DNA binding DNA-directed 5'-3' RNA polymerase activity protein binding RNA polymerase I activity RNA polymerase II activity RNA polymerase III activity	RPB5 (S. cerevisiae) rpb-5 (C. elegans) Rpb5 (D. melanogaster)
CDK4	ENSG00000135446	melanoma	PALBOCICLIB	cyclin-dependent protein serine/threonine kinase activity protein binding ATP binding cyclin-dependent protein serine/threonine kinase regulator activity cyclin binding protein complex binding protein serine/threonine kinase activity	CDC28 (S. cerevisiae) cdk-4 (C. elegans) Cdk4 (D. melanogaster)