CDK4

ENSG00000135446 - H. sapiens

Pathways

Go term Description
GO:0004693 cyclin-dependent protein serine/threonine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
GO:0030332 cyclin binding
GO:0032403 protein complex binding
GO:0004674 protein serine/threonine kinase activity

Drugs

Drug name Description
PALBOCICLIB CDK4/cyclin D1 inhibitor

Diseases

Disease Name
melanoma

Orthologs

Gene Organism
CDC28 S. cerevisiae
cdk-4 C. elegans
Cdk4 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000135446 CDK4 ENSG00000185386 MAPK11 H. sapiens SDL Slorth 0.954783 View
ENSG00000135446 CDK4 ENSG00000177981 ASB8 H. sapiens SDL Slorth 0.95476 View
ENSG00000073969 NSF ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.954557 View
ENSG00000135446 CDK4 ENSG00000139687 RB1 H. sapiens SSL Slorth 0.954547 View
ENSG00000135446 CDK4 ENSG00000149136 SSRP1 H. sapiens SDL Slorth 0.954487 View
ENSG00000131747 TOP2A ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.954484 View
ENSG00000102978 POLR2C ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.954389 View
ENSG00000082146 STRADB ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.954351 View
ENSG00000023445 BIRC3 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.954342 View
ENSG00000135446 CDK4 ENSG00000197442 MAP3K5 H. sapiens SSL Slorth 0.954039 View
ENSG00000135446 CDK4 ENSG00000158828 PINK1 H. sapiens SSL Slorth 0.954024 View
ENSG00000127586 CHTF18 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.953981 View
ENSG00000135446 CDK4 ENSG00000166598 HSP90B1 H. sapiens SSL Slorth 0.953707 View
ENSG00000131508 UBE2D2 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.953697 View
ENSG00000085449 WDFY1 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.953636 View
ENSG00000135446 CDK4 ENSG00000143776 CDC42BPA H. sapiens SDL Slorth 0.953501 View
ENSG00000077721 UBE2A ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.953495 View
ENSG00000135446 CDK4 ENSG00000173473 SMARCC1 H. sapiens SSL Slorth 0.953394 View
ENSG00000112679 DUSP22 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.953254 View
ENSG00000105173 CCNE1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.953253 View
ENSG00000055332 EIF2AK2 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.953175 View
ENSG00000082898 XPO1 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.953175 View
ENSG00000109320 NFKB1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.953054 View
ENSG00000135446 CDK4 ENSG00000138668 HNRNPD H. sapiens SSL Slorth 0.95305 View
ENSG00000135446 CDK4 ENSG00000158402 CDC25C H. sapiens SDL Slorth 0.953 View
ENSG00000097007 ABL1 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.952871 View
ENSG00000135446 CDK4 ENSG00000184012 TMPRSS2 H. sapiens SDL Slorth 0.952862 View
ENSG00000135446 CDK4 ENSG00000186575 NF2 H. sapiens SSL Slorth 0.952707 View
ENSG00000135446 CDK4 ENSG00000168496 FEN1 H. sapiens SDL Slorth 0.952667 View
ENSG00000126561 STAT5A ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.952522 View
ENSG00000101412 E2F1 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.952439 View
ENSG00000135446 CDK4 ENSG00000168385 SEPT2 H. sapiens SDL Slorth 0.952439 View
ENSG00000135446 CDK4 ENSG00000166913 YWHAB H. sapiens SSL Slorth 0.952414 View
ENSG00000105290 APLP1 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.952414 View
ENSG00000135446 CDK4 ENSG00000151692 RNF144A H. sapiens SDL Slorth 0.95241 View
ENSG00000053900 ANAPC4 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.952356 View
ENSG00000118260 CREB1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.952345 View
ENSG00000116044 NFE2L2 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.952338 View
ENSG00000135446 CDK4 ENSG00000170345 FOS H. sapiens SDL Slorth 0.952252 View
ENSG00000077097 TOP2B ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.952158 View