ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000167778 SPRYD3 H. sapiens SDL Slorth 0.944458 View
ENSG00000091831 ESR1 ENSG00000100731 PCNX1 H. sapiens SDL Slorth 0.944458 View
ENSG00000091831 ESR1 ENSG00000149257 SERPINH1 H. sapiens SDL Slorth 0.944458 View
ENSG00000091831 ESR1 ENSG00000197136 PCNX3 H. sapiens SDL Slorth 0.944458 View
ENSG00000091831 ESR1 ENSG00000132746 ALDH3B2 H. sapiens SDL Slorth 0.944458 View
ENSG00000091831 ESR1 ENSG00000137269 LRRC1 H. sapiens SDL Slorth 0.944458 View
ENSG00000091831 ESR1 ENSG00000101335 MYL9 H. sapiens SDL Slorth 0.944458 View
ENSG00000091831 ESR1 ENSG00000180957 PITPNB H. sapiens SDL Slorth 0.944458 View
ENSG00000091831 ESR1 ENSG00000149657 LSM14B H. sapiens SDL Slorth 0.944458 View
ENSG00000091831 ESR1 ENSG00000196950 SLC39A10 H. sapiens SDL Slorth 0.944458 View
ENSG00000091831 ESR1 ENSG00000182054 IDH2 H. sapiens SDL Slorth 0.944458 View
ENSG00000091831 ESR1 ENSG00000137693 YAP1 H. sapiens SSL Slorth 0.944413 View
ENSG00000091831 ESR1 ENSG00000131711 MAP1B H. sapiens SSL Slorth 0.944363 View
ENSG00000091831 ESR1 ENSG00000122692 SMU1 H. sapiens SSL Slorth 0.944344 View
ENSG00000091831 ESR1 ENSG00000108946 PRKAR1A H. sapiens SSL Slorth 0.944267 View
ENSG00000091831 ESR1 ENSG00000164867 NOS3 H. sapiens SSL Slorth 0.944237 View
ENSG00000091831 ESR1 ENSG00000117450 PRDX1 H. sapiens SSL Slorth 0.94423 View
ENSG00000091831 ESR1 ENSG00000128595 CALU H. sapiens SDL Slorth 0.944224 View
ENSG00000091831 ESR1 ENSG00000162367 TAL1 H. sapiens SSL Slorth 0.944209 View
ENSG00000091831 ESR1 ENSG00000196591 HDAC2 H. sapiens SDL Slorth 0.944202 View
ENSG00000091831 ESR1 ENSG00000099956 SMARCB1 H. sapiens SSL Slorth 0.944165 View
ENSG00000091831 ESR1 ENSG00000174231 PRPF8 H. sapiens SDL Slorth 0.944146 View
ENSG00000091831 ESR1 ENSG00000108984 MAP2K6 H. sapiens SSL Slorth 0.944118 View
ENSG00000091831 ESR1 ENSG00000104320 NBN H. sapiens SSL Slorth 0.944099 View
ENSG00000091831 ESR1 ENSG00000158169 FANCC H. sapiens SSL Slorth 0.944091 View
ENSG00000091831 ESR1 ENSG00000129204 USP6 H. sapiens SDL Slorth 0.944089 View
ENSG00000091831 ESR1 ENSG00000168148 HIST3H3 H. sapiens SSL Slorth 0.944079 View
ENSG00000091831 ESR1 ENSG00000136827 TOR1A H. sapiens SDL Slorth 0.944032 View
ENSG00000091831 ESR1 ENSG00000123124 WWP1 H. sapiens SSL Slorth 0.943929 View
ENSG00000091831 ESR1 ENSG00000127511 SIN3B H. sapiens SSL Slorth 0.943927 View
ENSG00000091831 ESR1 ENSG00000184787 UBE2G2 H. sapiens SDL Slorth 0.943922 View
ENSG00000085224 ATRX ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.943896 View
ENSG00000091831 ESR1 ENSG00000111276 CDKN1B H. sapiens SSL Slorth 0.943834 View
ENSG00000091831 ESR1 ENSG00000092010 PSME1 H. sapiens SDL Slorth 0.943772 View
ENSG00000091831 ESR1 ENSG00000163743 RCHY1 H. sapiens SSL Slorth 0.943761 View
ENSG00000091831 ESR1 ENSG00000113558 SKP1 H. sapiens SDL Slorth 0.94372 View
ENSG00000034053 APBA2 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.943694 View
ENSG00000091831 ESR1 ENSG00000123349 PFDN5 H. sapiens SSL Slorth 0.943693 View
ENSG00000091831 ESR1 ENSG00000185379 RAD51D H. sapiens SDL Slorth 0.943631 View
ENSG00000091831 ESR1 ENSG00000101868 POLA1 H. sapiens SSL Slorth 0.943621 View