ESR1

ENSG00000091831 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 core promoter sequence-specific DNA binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003682 chromatin binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0030235 nitric-oxide synthase regulator activity
GO:0030284 estrogen receptor activity
GO:0034056 estrogen response element binding
GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
GO:0042802 identical protein binding
GO:0051117 ATPase binding

Drugs

Drug name Description
BAZEDOXIFENE Estrogen receptor modulator
DIENESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL Estrogen receptor alpha agonist
DIETHYLSTILBESTROL DIPHOSPHATE Estrogen receptor agonist
ENCLOMIPHENE Estrogen receptor alpha modulator
ESTRADIOL Estrogen receptor alpha agonist
ESTRADIOL ACETATE Estrogen receptor alpha agonist
ESTRADIOL CYPIONATE Estrogen receptor alpha agonist
ESTRADIOL VALERATE Estrogen receptor alpha agonist
ESTROGENS, CONJUGATED Estrogen receptor agonist
ESTROGENS, CONJUGATED SYNTHETIC A Estrogen receptor agonist
ESTROGENS, ESTERIFIED Estrogen receptor agonist
ESTRONE Estrogen receptor alpha agonist
ESTRONE SULFURIC ACID Estrogen receptor alpha agonist
ETHINYL ESTRADIOL Estrogen receptor alpha agonist
FULVESTRANT Estrogen receptor antagonist
MESTRANOL Estrogen receptor alpha agonist
OSPEMIFENE Estrogen receptor modulator
POLYESTRADIOL PHOSPHATE Estrogen receptor alpha agonist
QUINESTROL Estrogen receptor agonist
RALOXIFENE
SYNTHETIC CONJUGATED ESTROGENS, B Estrogen receptor agonist
TAMOXIFEN Estrogen receptor alpha modulator
TOREMIFENE Estrogen receptor modulator

Diseases

Disease Name
breast

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000091831 ESR1 ENSG00000198380 GFPT1 H. sapiens SDL Slorth 0.945344 View
ENSG00000091831 ESR1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.945342 View
ENSG00000091831 ESR1 ENSG00000185386 MAPK11 H. sapiens SDL Slorth 0.945336 View
ENSG00000091831 ESR1 ENSG00000120616 EPC1 H. sapiens SSL Slorth 0.945272 View
ENSG00000079999 KEAP1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.945254 View
ENSG00000091831 ESR1 ENSG00000177169 ULK1 H. sapiens SDL Slorth 0.945228 View
ENSG00000070831 CDC42 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.945176 View
ENSG00000091831 ESR1 ENSG00000123562 MORF4L2 H. sapiens SSL Slorth 0.945121 View
ENSG00000091831 ESR1 ENSG00000184009 ACTG1 H. sapiens SSL Slorth 0.94506 View
ENSG00000091831 ESR1 ENSG00000108840 HDAC5 H. sapiens SDL Slorth 0.945014 View
ENSG00000091831 ESR1 ENSG00000153558 FBXL2 H. sapiens SDL Slorth 0.944891 View
ENSG00000091831 ESR1 ENSG00000120705 ETF1 H. sapiens SSL Slorth 0.944891 View
ENSG00000091831 ESR1 ENSG00000125630 POLR1B H. sapiens SSL Slorth 0.944884 View
ENSG00000091831 ESR1 ENSG00000111653 ING4 H. sapiens SSL Slorth 0.944882 View
ENSG00000091831 ESR1 ENSG00000141030 COPS3 H. sapiens SSL Slorth 0.944802 View
ENSG00000091831 ESR1 ENSG00000185591 SP1 H. sapiens SDL Slorth 0.94479 View
ENSG00000091831 ESR1 ENSG00000198382 UVRAG H. sapiens SDL Slorth 0.944786 View
ENSG00000091831 ESR1 ENSG00000115325 DOK1 H. sapiens SSL Slorth 0.944775 View
ENSG00000091831 ESR1 ENSG00000176749 CDK5R1 H. sapiens SSL Slorth 0.944692 View
ENSG00000091831 ESR1 ENSG00000105974 CAV1 H. sapiens SSL Slorth 0.944677 View
ENSG00000091831 ESR1 ENSG00000131759 RARA H. sapiens SSL Slorth 0.944661 View
ENSG00000069869 NEDD4 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.944658 View
ENSG00000091831 ESR1 ENSG00000134899 ERCC5 H. sapiens SSL Slorth 0.944584 View
ENSG00000058056 USP13 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.944562 View
ENSG00000091831 ESR1 ENSG00000124214 STAU1 H. sapiens SSL Slorth 0.944534 View
ENSG00000091831 ESR1 ENSG00000187627 RGPD1 H. sapiens SDL Slorth 0.944458 View
ENSG00000091831 ESR1 ENSG00000239900 ADSL H. sapiens SDL Slorth 0.944458 View
ENSG00000091831 ESR1 ENSG00000277075 HIST1H2AE H. sapiens SDL Slorth 0.944458 View
ENSG00000091831 ESR1 ENSG00000197409 HIST1H3D H. sapiens SDL Slorth 0.944458 View
ENSG00000091831 ESR1 ENSG00000196862 RGPD4 H. sapiens SDL Slorth 0.944458 View
ENSG00000091831 ESR1 ENSG00000153165 RGPD3 H. sapiens SDL Slorth 0.944458 View
ENSG00000091831 ESR1 ENSG00000174840 PDE12 H. sapiens SDL Slorth 0.944458 View
ENSG00000091831 ESR1 ENSG00000103160 HSDL1 H. sapiens SDL Slorth 0.944458 View
ENSG00000091831 ESR1 ENSG00000101104 PABPC1L H. sapiens SDL Slorth 0.944458 View
ENSG00000091831 ESR1 ENSG00000106066 CPVL H. sapiens SDL Slorth 0.944458 View
ENSG00000091831 ESR1 ENSG00000166965 RCCD1 H. sapiens SDL Slorth 0.944458 View
ENSG00000091831 ESR1 ENSG00000129003 VPS13C H. sapiens SDL Slorth 0.944458 View
ENSG00000091831 ESR1 ENSG00000174740 PABPC5 H. sapiens SDL Slorth 0.944458 View
ENSG00000091831 ESR1 ENSG00000197238 HIST1H4J H. sapiens SDL Slorth 0.944458 View
ENSG00000091831 ESR1 ENSG00000169629 RGPD8 H. sapiens SDL Slorth 0.944458 View