LRP6 - KDR

H. sapiens

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
LRP6 ENSG00000070018

No diseases in record

No drugs in record

low-density lipoprotein receptor activity
receptor binding
frizzled binding
protein binding
Wnt-protein binding
kinase inhibitor activity
toxin transporter activity
apolipoprotein binding
identical protein binding
protein homodimerization activity
Wnt-activated receptor activity
coreceptor activity involved in Wnt signaling pathway
coreceptor activity involved in canonical Wnt signaling pathway
arr (D. melanogaster)
KDR ENSG00000128052 NSCLC
angiosarcoma
melanoma
AXITINIB
CABOZANTINIB
LENVATINIB
NINTEDANIB
PAZOPANIB
PONATINIB
RAMUCIRUMAB
REGORAFENIB
SORAFENIB
SUNITINIB
VANDETANIB
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
signal transducer, downstream of receptor, with protein tyrosine kinase activity
vascular endothelial growth factor-activated receptor activity
integrin binding
protein binding
ATP binding
growth factor binding
Hsp90 protein binding
Pvr (D. melanogaster)