FLT4 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
FLT4	ENSG00000037280	soft tissue sarcoma	AXITINIB LENVATINIB NINTEDANIB PAZOPANIB REGORAFENIB SORAFENIB SUNITINIB VANDETANIB	transmembrane receptor protein tyrosine kinase activity vascular endothelial growth factor-activated receptor activity protein binding ATP binding growth factor binding protein phosphatase binding	Pvr (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)