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Slorth
KDR - BRAF
H. sapiens
SSL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
KDR
ENSG00000128052
NSCLC
angiosarcoma
melanoma
AXITINIB
CABOZANTINIB
LENVATINIB
NINTEDANIB
PAZOPANIB
PONATINIB
RAMUCIRUMAB
REGORAFENIB
SORAFENIB
SUNITINIB
VANDETANIB
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
signal transducer, downstream of receptor, with protein tyrosine kinase activity
vascular endothelial growth factor-activated receptor activity
integrin binding
protein binding
ATP binding
growth factor binding
Hsp90 protein binding
Pvr (D. melanogaster)
BRAF
ENSG00000157764
melanoma
colorectal
papillary thyroid
borderline ovarian
NSCLC
cholangiocarcinoma
pilocytic astrocytoma
Spitzoid tumour
pancreas acinar carcinoma
melanocytic nevus
prostate
gastric
DABRAFENIB
REGORAFENIB
SORAFENIB
VEMURAFENIB
protein kinase activity
protein serine/threonine kinase activity
MAP kinase kinase kinase activity
calcium ion binding
protein binding
ATP binding
mitogen-activated protein kinase kinase binding
identical protein binding
protein heterodimerization activity
small GTPase binding
lin-45 (C. elegans)