LRP6 - KIT

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
LRP6	ENSG00000070018	No diseases in record	No drugs in record	low-density lipoprotein receptor activity receptor binding frizzled binding protein binding Wnt-protein binding kinase inhibitor activity toxin transporter activity apolipoprotein binding identical protein binding protein homodimerization activity Wnt-activated receptor activity coreceptor activity involved in Wnt signaling pathway coreceptor activity involved in canonical Wnt signaling pathway	arr (D. melanogaster)
KIT	ENSG00000157404	GIST AML TGCT mastocytosis mucosal melanoma epithelioma	CABOZANTINIB DASATINIB IMATINIB LENVATINIB PAZOPANIB PONATINIB REGORAFENIB SORAFENIB SUNITINIB	protease binding protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity stem cell factor receptor activity Ras guanyl-nucleotide exchange factor activity protein binding ATP binding cytokine binding protein homodimerization activity metal ion binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity	Pvr (D. melanogaster)