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Genes
Gene:
Organism:
H. sapiens
S. cerevisiae
S. pombe
D. melanogaster
C. elegans
Type:
SSL
SDL
Quality:
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High Quality Predictions
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Experimentally Validated
Cancer:
Cancer gene:
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Druggable:
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Gene
Ensembl ID
Organism
Diseases
Drugs
Ontology
Interactions
PDGFRA
ENSG00000134853
H. sapiens
GIST
idiopathic hypereosinophilic syndrome
paediatric glioblastoma
BECAPLERMIN
LENVATINIB
NINTEDANIB
PAZOPANIB
PONATINIB
REGORAFENIB
SUNITINIB
protein kinase activity
transmembrane receptor protein tyrosine kinase activity
platelet-derived growth factor alpha-receptor activity
...
414
PDRG1
ENSG00000088356
H. sapiens
unfolded protein binding
...
5
PDSS2
ENSG00000164494
H. sapiens
protein heterodimerization activity
trans-octaprenyltranstransferase activity
trans-hexaprenyltranstransferase activity
...
3
PELO
ENSG00000152684
H. sapiens
endonuclease activity
protein binding
ribosome binding
...
240
PFAS
ENSG00000178921
H. sapiens
phosphoribosylformylglycinamidine synthase activity
ATP binding
metal ion binding
...
243
PFKFB1
ENSG00000158571
H. sapiens
6-phosphofructo-2-kinase activity
fructose-2,6-bisphosphate 2-phosphatase activity
protein binding
...
3
PGD
ENSG00000142657
H. sapiens
phosphogluconate dehydrogenase (decarboxylating) activity
phosphogluconate dehydrogenase (decarboxylating) activity
...
7
PGK1
ENSG00000102144
H. sapiens
phosphoglycerate kinase activity
protein binding
ATP binding
...
25
PHB2
ENSG00000215021
H. sapiens
protein binding
protein C-terminus binding
estrogen receptor binding
...
263
PHC1
ENSG00000111752
H. sapiens
DNA binding
zinc ion binding
...
3
PHC2
ENSG00000134686
H. sapiens
DNA binding
protein binding
zinc ion binding
...
219
PHC3
ENSG00000173889
H. sapiens
DNA binding
protein binding
zinc ion binding
...
2
PHF2
ENSG00000197724
H. sapiens
iron ion binding
protein binding
zinc ion binding
...
2
PHF8
ENSG00000172943
H. sapiens
chromatin binding
iron ion binding
protein binding
...
2
PI4KB
ENSG00000143393
H. sapiens
1-phosphatidylinositol 4-kinase activity
protein binding
ATP binding
...
2
PIK3CA
ENSG00000121879
H. sapiens
colorectal
gastric
glioblastoma
breast
protein serine/threonine kinase activity
protein binding
ATP binding
...
501
PIK3CB
ENSG00000051382
H. sapiens
SCC
NSCLC
protein binding
ATP binding
kinase activity
...
414
PIK3CD
ENSG00000171608
H. sapiens
IDELALISIB
protein binding
ATP binding
kinase activity
...
224
PIK3CG
ENSG00000105851
H. sapiens
protein kinase activity
protein serine/threonine kinase activity
protein binding
...
14
PIK3R1
ENSG00000145675
H. sapiens
glioblastoma
ovarian
colorectal
transmembrane receptor protein tyrosine kinase adaptor activity
insulin receptor binding
insulin-like growth factor receptor binding
...
3
PIKFYVE
ENSG00000115020
H. sapiens
1-phosphatidylinositol-3-phosphate 5-kinase activity
protein binding
ATP binding
...
145
PIM1
ENSG00000137193
H. sapiens
NHL
protein serine/threonine kinase activity
protein binding
ATP binding
...
183
PIM2
ENSG00000102096
H. sapiens
protein serine/threonine kinase activity
protein binding
ATP binding
...
4
PITRM1
ENSG00000107959
H. sapiens
metalloendopeptidase activity
enzyme activator activity
zinc ion binding
...
36
PLA2G2E
ENSG00000188784
H. sapiens
phospholipase A2 activity
calcium ion binding
...
2
PMF1
ENSG00000160783
H. sapiens
transcription coactivator activity
protein binding
leucine zipper domain binding
...
16
PMVK
ENSG00000163344
H. sapiens
phosphomevalonate kinase activity
ATP binding
...
2
PNISR
ENSG00000132424
H. sapiens
...
4
PNN
ENSG00000100941
H. sapiens
DNA binding
structural molecule activity
...
7
POLA1
ENSG00000101868
H. sapiens
CLOFARABINE
CLOFARABINE
CYTARABINE
FLUDARABINE PHOSPHATE
GEMCITABINE
NELARABINE
nucleotide binding
nucleoside binding
DNA binding
...
3258
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