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Genes
Gene:
Organism:
H. sapiens
S. cerevisiae
S. pombe
D. melanogaster
C. elegans
Type:
SSL
SDL
Quality:
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Experimentally Validated
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Cancer gene:
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Gene
Ensembl ID
Organism
Diseases
Drugs
Ontology
Interactions
POLD1
ENSG00000062822
H. sapiens
CRC
CLOFARABINE
CLOFARABINE
CYTARABINE
FLUDARABINE PHOSPHATE
GEMCITABINE
nucleotide binding
DNA binding
chromatin binding
...
3493
POLD3
ENSG00000077514
H. sapiens
DNA-directed DNA polymerase activity
protein binding
...
7
POLE
ENSG00000177084
H. sapiens
colorectal carcinoma
endometrioid carcinoma
stomach carcinoma
skin cancer
colorectal cancer susceptibility
CLOFARABINE
CLOFARABINE
CYTARABINE
FLUDARABINE PHOSPHATE
GEMCITABINE
nucleotide binding
DNA binding
chromatin binding
...
552
POLE2
ENSG00000100479
H. sapiens
DNA binding
DNA-directed DNA polymerase activity
protein binding
...
7
POLE3
ENSG00000148229
H. sapiens
DNA binding
DNA-directed DNA polymerase activity
protein binding
...
191
POLN
ENSG00000130997
H. sapiens
DNA binding
DNA-directed DNA polymerase activity
protein binding
...
12
POLR2B
ENSG00000047315
H. sapiens
DNA binding
chromatin binding
protein binding
...
1583
POLR2K
ENSG00000147669
H. sapiens
DNA binding
zinc ion binding
RNA polymerase I activity
...
139
POLR3A
ENSG00000148606
H. sapiens
DNA binding
chromatin binding
DNA-directed 5'-3' RNA polymerase activity
...
1039
POLR3B
ENSG00000013503
H. sapiens
DNA binding
ribonucleoside binding
metal ion binding
...
269
POMC
ENSG00000115138
H. sapiens
G-protein coupled receptor binding
receptor binding
hormone activity
...
7
PPAT
ENSG00000128059
H. sapiens
AZATHIOPRINE
AZATHIOPRINE
MERCAPTOPURINE
MERCAPTOPURINE
amidophosphoribosyltransferase activity
metal ion binding
4 iron, 4 sulfur cluster binding
...
98
PPCS
ENSG00000127125
H. sapiens
phosphopantothenate--cysteine ligase activity
phosphopantothenate--cysteine ligase activity
...
8
PPIE
ENSG00000084072
H. sapiens
nucleotide binding
RNA binding
peptidyl-prolyl cis-trans isomerase activity
...
88
PPME1
ENSG00000214517
H. sapiens
protein phosphatase inhibitor activity
protein phosphatase regulator activity
protein kinase binding
...
243
PPP1CC
ENSG00000186298
H. sapiens
phosphoprotein phosphatase activity
protein serine/threonine phosphatase activity
protein binding
...
58
PPP2R1A
ENSG00000105568
H. sapiens
clear cell ovarian carcinoma
antigen binding
protein serine/threonine phosphatase activity
protein binding
...
1785
PPP2R2A
ENSG00000221914
H. sapiens
protein serine/threonine phosphatase activity
protein binding
protein phosphatase regulator activity
...
334
PPWD1
ENSG00000113593
H. sapiens
peptidyl-prolyl cis-trans isomerase activity
...
6
PRIM2
ENSG00000146143
H. sapiens
single-stranded DNA binding
DNA-directed DNA polymerase activity
DNA primase activity
...
9
PRKAA1
ENSG00000132356
H. sapiens
chromatin binding
protein kinase activity
AMP-activated protein kinase activity
...
337
PRKAR1A
ENSG00000108946
H. sapiens
papillary thyroid
myxoma
endocrine
cAMP-dependent protein kinase inhibitor activity
protein binding
cAMP-dependent protein kinase regulator activity
...
234
PRKCD
ENSG00000163932
H. sapiens
protein kinase activity
protein serine/threonine kinase activity
protein kinase C activity
...
1391
PRKCZ
ENSG00000067606
H. sapiens
protein kinase activity
protein serine/threonine kinase activity
protein kinase C activity
...
531
PRKDC
ENSG00000253729
H. sapiens
double-stranded DNA binding
protein kinase activity
protein serine/threonine kinase activity
...
1571
PRMT5
ENSG00000100462
H. sapiens
core promoter sequence-specific DNA binding
transcription corepressor activity
protein binding
...
212
PRODH
ENSG00000100033
H. sapiens
proline dehydrogenase activity
FAD binding
...
4
PRPF18
ENSG00000165630
H. sapiens
second spliceosomal transesterification activity
...
34
PRSS8
ENSG00000052344
H. sapiens
serine-type endopeptidase activity
protein binding
serine-type peptidase activity
...
4
PSMB6
ENSG00000142507
H. sapiens
endopeptidase activity
threonine-type endopeptidase activity
cadherin binding involved in cell-cell adhesion
...
65
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